{"created":"2023-05-15T14:57:27.196149+00:00","id":77966,"links":{},"metadata":{"_buckets":{"deposit":"d854bda3-ee1a-4101-9d36-d47a358a6b7c"},"_deposit":{"created_by":1,"id":"77966","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"77966"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00077966","sets":["10:29"]},"author_link":["813124","813116","813123","813126","813117","813127","813128","813122","813120","813125","813121","813115","813118","813119"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-12-11","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"全身に転移したがんの治療法として、アルファ線を放出する放射性同位元素（RI）を組み込んだ薬剤あるいはRIそのものを体内に投与し、がん細胞に送り届ける、アルファ線放出RI内用療法が注目されている。我々は、アルファ線がん治療薬211At-MABGを用いた非臨床試験を進め、優れた抗腫瘍効果を明らかにしてきた。現在、211At-MABGの殺細胞メカニズムの解明に取り組んでいる。本発表では、RNAシーケンス解析により明らかとなった211At-MABGの殺細胞メカニズムと211At-MABG特異的な応答について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"QST高崎サイエンスフェスタ2019","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"坂下, 哲哉"}],"nameIdentifiers":[{"nameIdentifier":"813115","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大島, 康宏"}],"nameIdentifiers":[{"nameIdentifier":"813116","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野, 暢明"}],"nameIdentifiers":[{"nameIdentifier":"813117","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"横田, 裕一郎"}],"nameIdentifiers":[{"nameIdentifier":"813118","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡辺, 茂樹"}],"nameIdentifiers":[{"nameIdentifier":"813119","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐々木, 一郎"}],"nameIdentifiers":[{"nameIdentifier":"813120","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒川, 和晴"}],"nameIdentifiers":[{"nameIdentifier":"813121","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石岡, 典子"}],"nameIdentifiers":[{"nameIdentifier":"813122","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakashita, Tetsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813123","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oshima, Yasuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813124","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokota, Yuuichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813125","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Shigeki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813126","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sasaki, Ichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813127","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishioka, Noriko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"813128","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"アルファ線がん治療薬に対する細胞の応答メカニズム ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"アルファ線がん治療薬に対する細胞の応答メカニズム "},{"subitem_title":"―次世代シーケンス解析による新発見―","subitem_title_language":"en"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-12-09"},"publish_date":"2019-12-09","publish_status":"0","recid":"77966","relation_version_is_last":true,"title":["アルファ線がん治療薬に対する細胞の応答メカニズム "],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:31:15.835010+00:00"}