@misc{oai:repo.qst.go.jp:00077812,
 author = {Konishi, Teruaki and Kobayashi, Alisa and Ohsawa, Daisuke and Oikawa, Masakazu and Konishi, Teruaki and Kobayashi, Alisa and Ohsawa, Daisuke and Oikawa, Masakazu},
 month = {Dec},
 note = {Advanced microbeam irradiation system made possible to deliver a defined amount of radiation on a single cell with a few micro-meter resolution. Our microbeam, the Single-Particle Irradiation system to CEll (SPICE) provides a 3.4 MeV proton microbeam focused with a quadrupole magnetic lens on an upward vertical beam line. SPICE is the only proton microbeam in Japan that can target nucleus, cytoplasm, or both with high throughput, high targeting accuracy along with promising stability. In this presentation, the state-of-the-art features of SPICE will be introduced along with our recent results from single cell analysis of microbeam targeted cells on defensive signalling through intra-cellular response against radiation, such as nucleus and cytoplasmic damage response., 3rd QST International Symposium on Quantum Life Science},
 title = {Advanced microbeam technology for single cell radiation biology},
 year = {2019}
}