@article{oai:repo.qst.go.jp:00077720,
 author = {Chen, Zhen and Mori, Wakana and Fu, Hualong and A. Schafroth, Michael and Hatori, Akiko and Shao, Tuo and Zhang, Genwei and S. Van, Richard and Zhang, Yiding and Hu, Kuan and Fujinaga, Masayuki and Ming-Rong, Zhang and Wakana, Mori and Akiko, Hatori and Zhang, Yiding and Kuan, Hu and Masayuki, Fujinaga and Zhang, Ming-Rong},
 issue = {19},
 journal = {Journal of Medicinal Chemistry},
 month = {Sep},
 note = {Dysfunction of monoacylglycerol lipase (MAGL) is associated with several
psychopathological disorders, including drug addiction and neurodegenerative diseases. Herein we design, synthesize, and evaluate several irreversible fluorine-containing MAGL inhibitors for positron emission tomography (PET) ligand development. Compound 6 (identified from a therapeutic agent) was advanced for 18F-labeling via a novel spirocyclic iodonium ylide (SCIDY) strategy, which demonstrated high brain permeability and excellent specific binding. This work supports further development of novel 18F-labeled MAGL PET probes.},
 pages = {8866--8872},
 title = {Design, Synthesis, and Evaluation of 18F‑Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes},
 volume = {62},
 year = {2019}
}