{"created":"2023-05-15T14:57:13.747015+00:00","id":77663,"links":{},"metadata":{"_buckets":{"deposit":"c9fb49bc-d2d4-48e2-8623-3a32b7d686f1"},"_deposit":{"created_by":1,"id":"77663","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"77663"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00077663","sets":["10:28"]},"author_link":["817427","817423","817429","817430","817426","817433","817437","817435","817424","817422","817438","817441","817428","817432","817434","817442","817421","817431","817439","817436","817440","817425"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-11-21","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】現在、QST病院では、頭頸部腫瘍に対して、炭素線治療が行われている。頭頸部の治療では、脳や視神経などの正常組織が照射野に近接しており、治療後に脳障害や視神経障害等が発生する場合がある。その臨床解析には、dose volume histogram (DVH)等が利用されている。我々は原因究明や新たな予測因子として線量平均LETを計算するシステムを開発し、実際の症例を用いてその有用性を評価する。【方法】炭素線治療計画装置Heavy Ion Plan (HIPLAN)を利用して治療された症例を解析するために、線量平均LETおよびその標準偏差を算出する臨床解析ツールを開発し、HIPLANに実装した。そして、脳炎を発症した4症例や視神経に高線量が投与された2症例、脳炎を発症し、かつ視神経に高線量が投与されていた1症例、大きい腫瘍の再発2症例や非再発1症例の計10症例に対して、計算を実施し、LET volume histogramを用いて、再発および障害発生との関係性を解析した。【結果】HIPLANに臨床解析ツールを実装することで容易に計算し、解析できるようになった。そして、10症例に対して、線量平均LETを計算し、解析を実施した。再発および障害発生の原因究明に役立てるデータを示すためには、症例数を上げる必要があることがわかった。【結語】今回、線量平均LETとその標準偏差を求める計算システムを開発し、頭頸部症例に対して臨床解析を試みた。少数例であったため有意な結果は得られなかったが、今後は、もっと症例数を増やし、解析を継続していきたい。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線腫瘍学会第32回学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 淳史"}],"nameIdentifiers":[{"nameIdentifier":"817421","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sung Hyun, Lee"}],"nameIdentifiers":[{"nameIdentifier":"817422","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木優維"}],"nameIdentifiers":[{"nameIdentifier":"817423","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古市渉"}],"nameIdentifiers":[{"nameIdentifier":"817424","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊川, 裕明"}],"nameIdentifiers":[{"nameIdentifier":"817425","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金子, 崇"}],"nameIdentifiers":[{"nameIdentifier":"817426","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤, 昌志"}],"nameIdentifiers":[{"nameIdentifier":"817427","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅, 満喜人"}],"nameIdentifiers":[{"nameIdentifier":"817428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山岡, 恵士"}],"nameIdentifiers":[{"nameIdentifier":"817429","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"谷本, 克之"}],"nameIdentifiers":[{"nameIdentifier":"817430","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野, 良介"}],"nameIdentifiers":[{"nameIdentifier":"817431","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻, 比呂志"}],"nameIdentifiers":[{"nameIdentifier":"817432","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Atsushi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817433","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sung-Hyun, Lee","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817434","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikawa, Hiroaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817435","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kaneko, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817436","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817437","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suga, Makito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaoka, Keisi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanimoto, Katsuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kohno, Ryosuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"817442","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"頭頸部腫瘍に対する炭素線治療における線量平均LET計算","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"頭頸部腫瘍に対する炭素線治療における線量平均LET計算"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-11-27"},"publish_date":"2019-11-27","publish_status":"0","recid":"77663","relation_version_is_last":true,"title":["頭頸部腫瘍に対する炭素線治療における線量平均LET計算"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:23:53.995855+00:00"}