@article{oai:repo.qst.go.jp:00077565, author = {Katagiri, Ken and Wakui, Takashi and Hojo, Satoru and A Yu, Boytsov, and D. Donets, E. and E. Donets, E. and Yu. Ramzdorf, A. and Noda, Akira and Shirai, Toshiyuki and Noda, Koji and Ken, Katagiri and Takashi, Wakui and Satoru, Hojo and Akira, Noda and Toshiyuki, Shirai and Koji, Noda}, issue = {5}, journal = {Review of Scientific Instruments}, month = {May}, note = {The ion-production efficiency of a newly developed singly charged ion source (SCIS) has been investigated to discuss the possibility of it being used in an isotope separation on-line system that provides 11C ions for heavy-ion cancer therapy with simultaneous verification of the irradiation field using positron emission tomography. The SCIS uses a low-energy hollow electron beam to produce singly charged carbon ions efficiently. To deliver sufficient 11C ions to the treatment room from a limited amount of 11C molecules, which are produced from a boron compound target and proton-beam irradiation via the 11B(p,n)11C reaction, the SCIS must have high ion-production efficiency. To realize this high efficiency, the SCIS was designed using a three-dimensional particle-in-cell code in previous work. With the fabricated SCIS, we performed experiments to measure the efficiency of producing CO+2 ions from nonradioactive 12CO2 molecules and C+ ions from nonradioactive 12CH4 molecules. We found that the SCIS achieved efficiencies of εC+=4×10−3 (0.4%) for C+ production and εCO+2=0.107 (10.7%) for CO+2 production.}, title = {Ion-production efficiency of a singly charged ion source developed toward a 11C irradiation facility for cancer therapy}, volume = {90}, year = {2019} }