{"created":"2023-05-15T14:57:04.200580+00:00","id":77442,"links":{},"metadata":{"_buckets":{"deposit":"72806f30-f4b8-4417-ad7b-f7b0017bff54"},"_deposit":{"created_by":1,"id":"77442","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"77442"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00077442","sets":["10:29"]},"author_link":["802213","802208","802217","802211","802222","802212","802216","802220","802221","802224","802210","802223","802209","802214","802207","802225","802226","802215","802218","802219"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-11-02","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The alpha-emitting radiopharmaceutical meta-[211At]astatobenzylguanidine (211At-MABG) has potential as a metastatic pheochromocytoma treatment. As 211At-MABG does not emit gamma-rays suitable for dosimetry and imaging, 211At-MABG needs a companion diagnostic imaging agent such as meta-[123I]iodobenzylguanidine (123I-MIBG) to be used in making treatment decisions. We evaluated the similarities and differences between 123I-MIBG and 211At-MABG in biodistribution in normal mice. BALB/c mice were injected with 123I-MIBG or 211At-MABG, and the radioactivity levels (%ID/g) in the tissues were determined at 1 and 30 min, and 1, 3, 6, and 24 h after the injection.\nResults: 211At-MABG and 123I-MIBG showed very similar biodistribution profiles in normal mice at every time point. \nConclusions: 123I-MIBG can be used for dosimetry and imaging for decisions regarding treatment with 211At-MABG radiotherapy.\n","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第59回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"趙, 松吉"}],"nameIdentifiers":[{"nameIdentifier":"802207","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉永, 恵一郎"}],"nameIdentifiers":[{"nameIdentifier":"802208","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"粟生木, 美穂"}],"nameIdentifiers":[{"nameIdentifier":"802209","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"右近, 直之"}],"nameIdentifiers":[{"nameIdentifier":"802210","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"下山, 彩希"}],"nameIdentifiers":[{"nameIdentifier":"802211","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西嶋, 剣一"}],"nameIdentifiers":[{"nameIdentifier":"802212","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鷲山, 幸信"}],"nameIdentifiers":[{"nameIdentifier":"802213","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鷲野, 弘明"}],"nameIdentifiers":[{"nameIdentifier":"802214","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋, 和弘"}],"nameIdentifiers":[{"nameIdentifier":"802215","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"東, 達也"}],"nameIdentifiers":[{"nameIdentifier":"802216","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 浩"}],"nameIdentifiers":[{"nameIdentifier":"802217","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhao, Songji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802218","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshinaga, Keiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802219","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoki, Miho","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802220","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ukon, Naoyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802221","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishijima, Kenichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802222","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koushin, Washiyama","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802223","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Washino, Komei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802224","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Higashi, Tatsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802225","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"802226","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"正常マウスにおける123I-MIBGと211At-MABGの体内動態の評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"正常マウスにおける123I-MIBGと211At-MABGの体内動態の評価"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-11-15"},"publish_date":"2019-11-15","publish_status":"0","recid":"77442","relation_version_is_last":true,"title":["正常マウスにおける123I-MIBGと211At-MABGの体内動態の評価"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:45:05.824049+00:00"}