@article{oai:repo.qst.go.jp:00077350, author = {山口, 藍子(群馬大学) and Arifudin, Achmad(群馬大学) and 花岡, 宏史(群馬大学) and Yusri, Dwi Heryanto(群馬大学) and Anu, Bhattarai(群馬大学) and Ratianto(群馬大学) and Erdene, Khongorzul(群馬大学) and Rini, Shintawati(群馬大学) and Adhipatria, Kartamihardja(群馬大学) and 金井, 彩香(群馬大学) and 須郷, 由美 and 石岡, 典子 and 樋口, 徹也(群馬大学) and 対馬, 義人(群馬大学) and Yumi, Sugo and Noriko, Ishioka}, issue = {1}, journal = {BMC Cancer}, month = {Oct}, note = {This study aimed to investigate the potential of radiolabeled cetuximab as a non-invasive tool to predict cetuximab accumulation in NSCLC tumor xenografts with varying EGFR expression levels. Strong correlations were found between 64Cu-DOTA-cetuximab tumor uptake with EGFR expression level. PET imaging with 64Cu-DOTA-cetuximab allowed clear visualization of tumors. Our findings suggest that this immuno-PET imaging can be clinically translated as a tool to predict cetuximab accumulation in NSCLC cancer patients prior to cetuximab therapy.}, title = {Immuno-PET imaging for non-invasive assessment of cetuximab accumulation in non-small cell lung cancer}, volume = {19}, year = {2019} }