{"created":"2023-05-15T14:56:59.421450+00:00","id":77338,"links":{},"metadata":{"_buckets":{"deposit":"723b45eb-2382-49da-b604-03e6cee91641"},"_deposit":{"created_by":1,"id":"77338","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"77338"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00077338","sets":["10:29"]},"author_link":["799458","799468","799465","799472","799471","799469","799473","799461","799462","799464","799457","799467","799460","799456","799463","799470","799459","799466"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-11-02","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【背景・目的】 [18F]Fluoroethyl（FEt）化薬剤は、11C標識メチル化薬剤の前駆体から18F標識合成が可能であり、広く応用されている。[18F]FEt化合成については、2ポット合成法が主流であったが、近年Knieeらが1,2-Bis(tosyloxy)ethaneを用いた水存在下1ポット[18F]FEt化合成法を報告したため、改良した簡易的な[18F]FEDAC及び[18F]FET合成法を検討した。　【方法】[18F]FEDAC合成については、Sep-Pak QMAからK222及びK2CO3の入った2%水入りCH3CN溶液で[18F]F-を溶出し、炭酸セシウム存在下100℃、5分の反応で[18F]Fluoroethyl tosylateを合成し、前駆体/DMSO溶液を加え100℃で15分間反応させた。[18F]FETについては、NaOH存在下90℃で10分間反応させた。　　【結果】[18F]FEDAC合成については、約4 mgの前駆体を用いて18F-から18%以上の放射化学的収率で合成できた。[18F]FET合成については、約6 mgの前駆体を用いて18F-から10%以上の放射化学的収率で合成できた。　【結論】以前の合成法に比べ短時間で簡易的に[18F]FEDAC及び[18F]FETを合成することができた。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第59回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"河村, 和紀"}],"nameIdentifiers":[{"nameIdentifier":"799456","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"熊田, 勝志"}],"nameIdentifiers":[{"nameIdentifier":"799457","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森, 若菜"}],"nameIdentifiers":[{"nameIdentifier":"799458","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤永, 雅之"}],"nameIdentifiers":[{"nameIdentifier":"799459","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"栗原, 雄祐"}],"nameIdentifiers":[{"nameIdentifier":"799460","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小川, 政直"}],"nameIdentifiers":[{"nameIdentifier":"799461","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大久保, 崇之"}],"nameIdentifiers":[{"nameIdentifier":"799462","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"念垣, 信樹"}],"nameIdentifiers":[{"nameIdentifier":"799463","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張, 明栄"}],"nameIdentifiers":[{"nameIdentifier":"799464","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawamura, Kazunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kumata, Katsushi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mori, Wakana","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799467","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujinaga, Masayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kurihara, Yusuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Masanao","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799470","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohkubo, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nengaki, Nobuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799472","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ming-Rong, Zhang","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"799473","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference 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