@article{oai:repo.qst.go.jp:00077109, author = {Sakamoto, Ayako and Ayako, Sakamoto}, journal = {Frontiers in Plant Science}, month = {Oct}, note = {Plant genomes sustain various forms of DNA damage that stall replication forks. Translesion synthesis (TLS) is one of the pathways to overcome stalled replication, in which specific polymerases (TLS polymerase) perform bypass synthesis across DNA damage. This article gives a brief overview of plant TLS polymerases. In Arabisopsis, DNA polymerase (Pol) ζ, η, κ, θ, λ and Reversionless1 (Rev1) are shown to be involved in the TLS. In general, TLS polymerases have low fidelity and often induce mutations. Disruption of AtPolζ or AtRev1 reduces somatic mutation frequency, whereas disruption of AtPolη elevates it, suggesting that plants have both mutagenic and less mutagenic TLS activities. Hypersensitivities of TLS-deficient plants to γ-ray suggest that plant TLS polymerases have multiple roles.}, title = {Translesion synthesis in plants: ultraviolet resistance and beyond}, volume = {10}, year = {2019} }