@article{oai:repo.qst.go.jp:00076138,
 author = {Matsuo, Yoichiro and Izumi, Yoshinobu and Sakamoto, Ayako and Hase, Yoshihiro and Sato, Katsuya and Shimizu, Kikuo and Matsuo, Yoichiro and Izumi, Yoshinobu and Sakamoto, Ayako and Hase, Yoshihiro and Sato, Katsuya and Shimizu, Kikuo},
 issue = {3},
 journal = {Quantum Beam Science},
 month = {Jun},
 note = {Ion beams have several significantly interesting features, such as high biological effect and unique mutation spectrum. In this study, the effects of double strand breaks and 8-oxo-2'-deoxyguanosine (8-oxodG) caused by ion-beam irradiation were examined. We irradiated repair-gene-inactive strains rad52, ogg1, and msh2 using carbon ions beams, analyzed the lethality and characterized the mutations. The present observations suggested that nucleotide incorporation of oxidative damage gave only a limited effect on cell viability and genome fidelity. We also detected a hotspot at around +79 to +98 in URA3 in wild-type and mutant lines, suggesting the presence of a mutation-susceptible region.},
 title = {Molecular Analysis of Carbon Ion-Induced Mutations in DNA Repair-Deficient Strains of Saccharomyces cerevisiae},
 volume = {3},
 year = {2019}
}