{"created":"2023-05-15T14:55:53.240238+00:00","id":75890,"links":{},"metadata":{"_buckets":{"deposit":"cd6bdf13-fc5a-49df-b6d9-6d7690ab5f7a"},"_deposit":{"created_by":1,"id":"75890","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"75890"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00075890","sets":["10:28"]},"author_link":["823193","823194"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-05-23","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"放射線の生物影響研究のために放医研で樹立された温度感受性変異株を対象として、ゲノム安定性維持機構に関連する遺伝子を分離し、その機能を解析している。これまでの解析から、RNAポリメラーゼII の最大サブユニット(Rpb1)やスプライシング因子Smu1など、RNA代謝反応に関連する遺伝子の温度感受性変異が、姉妹染色分体交換の誘発など染色体不安定性を引き起こすことを明らかにしてきた。温度感受性変異株の特徴を活用し、ゲノム安定性維持機構に関連する遺伝子の機能の解明に取り組んでいる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"量子生命科学会第1回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"菅谷, 公彦"}],"nameIdentifiers":[{"nameIdentifier":"823193","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugaya, Kimihiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"823194","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"転写やスプライシングと染色体不安定性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"転写やスプライシングと染色体不安定性"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-24"},"publish_date":"2019-05-24","publish_status":"0","recid":"75890","relation_version_is_last":true,"title":["転写やスプライシングと染色体不安定性"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:15:23.947405+00:00"}