{"created":"2023-05-15T14:55:52.623899+00:00","id":75876,"links":{},"metadata":{"_buckets":{"deposit":"7a61c2b8-a019-4d1e-be9e-fdf6dc411afe"},"_deposit":{"created_by":1,"id":"75876","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"75876"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00075876","sets":["1"]},"author_link":["859756","859758","859753","859755","859757","859754"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"101","bibliographicPageStart":"98","bibliographicVolumeNumber":"183","bibliographic_titles":[{"bibliographic_title":"Radiation Protection Dosimetry"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"This study aimed to reveal the effect of X-irradiation on mitochondrial function in terms of mitochondrial membrane potential (ΔΨm) and ATP productivity. At the cellular level, ΔΨm was quantified using JC-1, a mitochondrial probe that emits red or green fluorescence at high or low ΔΨm sites, respectively. The fluorescence area was quantified for both colours together relative to the whole-cell area of the same cell. The fluorescence areas versus whole-cell areas varied widely among the irradiated cells depending on the X-ray doses received (6 and 10 Gy) and incubation time, although the relative red area to total mitochondrial area was rather constant. Average ATP concentrations temporarily increased and showed a maximum at 48 h after irradiation for largely G1-arrested cells. These results indicate that an increase of mitochondrial volume per cell, not simply an increase in their active sites, is induced by irradiation, resulting in enhanced ATP production.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1093/rpd/ncy254","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://academic.oup.com/rpd/article/183/1-2/98/5244128","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0144-8420","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"浜田, 涼"}],"nameIdentifiers":[{"nameIdentifier":"859753","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"神長, 輝一"}],"nameIdentifiers":[{"nameIdentifier":"859754","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 啓司"}],"nameIdentifiers":[{"nameIdentifier":"859755","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"横谷, 明徳"}],"nameIdentifiers":[{"nameIdentifier":"859756","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kaminaga, Kiichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"859757","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokoya, Akinari","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"859758","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"MITOCHONDRIAL MEMBRANE POTENTIAL, MORPHOLOGY AND ATP PRODUCTION IN MAMMALIAN CELLS EXPOSED TO X-RAYS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"MITOCHONDRIAL MEMBRANE POTENTIAL, MORPHOLOGY AND ATP PRODUCTION IN MAMMALIAN CELLS EXPOSED TO X-RAYS"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-22"},"publish_date":"2019-05-22","publish_status":"0","recid":"75876","relation_version_is_last":true,"title":["MITOCHONDRIAL MEMBRANE POTENTIAL, MORPHOLOGY AND ATP PRODUCTION IN MAMMALIAN CELLS EXPOSED TO X-RAYS"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:12:50.059460+00:00"}