@article{oai:repo.qst.go.jp:00075841, author = {Furusawa, Yoshiya and Matsumoto, Yoshitaka and Hirayama, Ryoichi and Ohsawa, Daisuke and Konishi, Teruaki and Furusawa, Yoshiya and Hirayama, Ryoichi and Ohsawa, Daisuke and Konishi, Teruaki}, issue = {1-2}, journal = {Radiation Protection Dosimetry}, month = {Dec}, note = {It is believed that the dose-rate of radiation will have an influence on cell sensitivity. The dose-rate effects on cell survival can be expressed by the change of the β term in the LQ model. The value at a high dose-rate decreases below 60 Gy/h and reaches zero at 0.2 Gy/h or less for photons. However, the effect for a high-LET ion-beam is not well known. At HIMAC, cells were exposed to 70 keV/µm carbon-ion beams at different dose-rates between 0.5 and 600 Gy/h at room temperature. The β values for all survival curves show no significant differences among the dose-rates tested for HSG, V79, and CHO cells. Changing the ion-beam dose-rate had no effect on cell survival. This suggests that high-LET particle beams, such as galactic cosmic rays, may not exhibit a dose-rate effect on cell survival. Low-dose-rate radiation showed an effect similar to high-dose-rate radiation.}, pages = {219--222}, title = {Dose-Rate and Cell Killing Sensitivity of High-Linear Energy Transfer Ion Beam}, volume = {183}, year = {2018} }