@article{oai:repo.qst.go.jp:00075840, author = {Konishi, Teruaki and Kodaira, Satoshi and Itakura, Yuichi and Ohsawa, Daisuke and Shino, Homma-Takeda and Teruaki, Konishi and Satoshi, Kodaira and Yuichi, Itakura and Daisuke, Ohsawa and Shino, Takeda}, issue = {1-2}, journal = {Radiation Protection Dosimetry}, month = {Dec}, note = {Uranium is renowned as a global contaminant, and attracts major concern with regards to the health risks involved because its nephrotoxicity. This paper discusses the development of a simple method to identify accumulated regions or localized sites of uranium within kidneys using the CR-39 plastic nuclear track detector. To demonstrate the proposed method, renal cryo-sections (5 μm-t) from Wistar male rats, subcutaneously administered with uranyl acetate (2 mg/kg), were prepared on day one after administration. Concerned sections were subsequently placed on CR-39, stored for 1.25 years, and then etched in a 7 M NaOH solution at 70 ℃ for 3 h. α-tracks were then detected in the form of etch pits, corresponding to uranium, and also the tissue shape and structure were transferred as a roughness on the surface of CR-39. As observed, the proposed method served to facilitate simultaneous detection and identification of localized regions of uranium accumulation within kidneys.}, pages = {242--246}, title = {Imaging uranium distribution on rat kidney sections through detection of alpha tracks using CR-39 plastic nuclear track detector}, volume = {183}, year = {2018} }