{"created":"2023-05-15T14:55:45.400308+00:00","id":75705,"links":{},"metadata":{"_buckets":{"deposit":"1772fb0b-5d69-4668-aef2-c05464818a8e"},"_deposit":{"created_by":1,"id":"75705","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"75705"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00075705","sets":["2"]},"author_link":["798328","798324","798329","798331","798326","798327","798325","798330","798332"],"item_10003_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"39","bibliographicPageStart":"36","bibliographicVolumeNumber":"183","bibliographic_titles":[{"bibliographic_title":"Radiation Protection Dosimetry"}]}]},"item_10003_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We applied circular dichroism (CD) spectral analysis to obtain the secondary structure of the DNA repair protein XRCC4, with a focus on its C-terminus. Using synchrotron radiation as a light source across a wide range of wavelengths, including vacuum ultraviolet light from 180 to 200 nm and ultraviolet light from 200 to 240 nm, we determined the secondary structure composition of the full-length protein, including its C-terminus, which had not yet been -the focus of crystallography studies, though it contains several phosphorylation sites. The secondary structures inferred using the obtained CD spectra indicate that the C-terminus is composed of a substantial fraction of turns with a few unordered and α-helix structures and almost no β-strands. The C-terminus is likely to form a characteristic secondary structure with turns as a main component, and its DNA repair function is likely regulated by the structural change induced by phosphorylation of the terminus.","subitem_description_type":"Abstract"}]},"item_10003_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford Academic"}]},"item_10003_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1093/rpd/ncy275","subitem_relation_type_select":"DOI"}}]},"item_10003_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://academic.oup.com/rpd/advance-article/doi/10.1093/rpd/ncy275/5250488","subitem_relation_type_select":"URI"}}]},"item_10003_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0144-8420","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"西久保, 開"}],"nameIdentifiers":[{"nameIdentifier":"798324","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"泉, 雄大"}],"nameIdentifiers":[{"nameIdentifier":"798325","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本義久"}],"nameIdentifiers":[{"nameIdentifier":"798326","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤井, 健太郎"}],"nameIdentifiers":[{"nameIdentifier":"798327","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松尾光一"}],"nameIdentifiers":[{"nameIdentifier":"798328","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"横谷, 明徳"}],"nameIdentifiers":[{"nameIdentifier":"798329","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishikubo, Kai","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"798330","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujii, Kentaro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"798331","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yokoya, Akinari","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"798332","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"STRUCTURAL ANALYSIS OF DNA REPAIR PROTEIN XRCC4 APPLYING CIRCULAR DICHROISM IN AN AQUEOUS SOLUTION","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"STRUCTURAL ANALYSIS OF DNA REPAIR PROTEIN XRCC4 APPLYING CIRCULAR DICHROISM IN AN AQUEOUS SOLUTION"}]},"item_type_id":"10003","owner":"1","path":["2"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-03-28"},"publish_date":"2019-03-28","publish_status":"0","recid":"75705","relation_version_is_last":true,"title":["STRUCTURAL ANALYSIS OF DNA REPAIR PROTEIN XRCC4 APPLYING CIRCULAR DICHROISM IN AN AQUEOUS SOLUTION"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:51:24.273457+00:00"}