@inproceedings{oai:repo.qst.go.jp:00075705,
 author = {西久保, 開 and 泉, 雄大 and 松本義久 and 藤井, 健太郎 and 松尾光一 and 横谷, 明徳 and Nishikubo, Kai and Fujii, Kentaro and Yokoya, Akinari},
 book = {Radiation Protection Dosimetry},
 issue = {1-2},
 month = {Dec},
 note = {We applied circular dichroism (CD) spectral analysis to obtain the secondary structure of the DNA repair protein XRCC4, with a focus on its C-terminus. Using synchrotron radiation as a light source across a wide range of wavelengths, including vacuum ultraviolet light from 180 to 200 nm and ultraviolet light from 200 to 240 nm, we determined the secondary structure composition of the full-length protein, including its C-terminus, which had not yet been -the focus of crystallography studies, though it contains several phosphorylation sites. The secondary structures inferred using the obtained CD spectra indicate that the C-terminus is composed of a substantial fraction of turns with a few unordered and α-helix structures and almost no β-strands. The C-terminus is likely to form a characteristic secondary structure with turns as a main component, and its DNA repair function is likely regulated by the structural change induced by phosphorylation of the terminus.},
 pages = {36--39},
 publisher = {Oxford Academic},
 title = {STRUCTURAL ANALYSIS OF DNA REPAIR PROTEIN XRCC4 APPLYING CIRCULAR DICHROISM IN AN AQUEOUS SOLUTION},
 volume = {183},
 year = {2018}
}