@misc{oai:repo.qst.go.jp:00075683,
 author = {Zou, Guangming and Pei, Hailong and Li, Bingyan and Furusawa, Yoshiya and Hirayama, Ryoichi and Konishi, Teruaki and Furusawa, Yoshiya and Hirayama, Ryoichi and Konishi, Teruaki},
 month = {Apr},
 note = {The dynamic interchange between monomeric globular actin (G-actin) and polymeric filamentous actin filaments (F-actin) is fundamental to cell motility and cytokinesis. However, there are few literatures elucidating the regulation of long noncoding RNAs (lncRNA) in -actin dynamic. Here we characterize a lncRNA: LNC CRYBG3 and we confirmed a physical and functional interaction between LNC CRYBG3 and -actin whichsuppresses G-actin polymerization. During HIMAC experiment, we found a heavy ion radiation sensitived LncRNA CRYBG3 and it’s overexpression caused tumor cells’ survival rate decreased for 72%. Therefore, we hypothesized that lncRNA CRYBG3 regulates heavy ion induced apoptosis by targeting Actin-MAL-SRF pathway., 平成30年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告会},
 title = {Function of non-coding RNAs in regulating heavy-ion induced biological effects.  (17J329-FY2018)},
 year = {2019}
}