@article{oai:repo.qst.go.jp:00075640,
 author = {Kuan, Hu and Hanyu, Masayuki and Xie, Lin and Zhang, Yiding and Nagatsu, Kotaro and Suzuki, Hisashi and Ming-Rong, Zhang and Kuan, Hu and Hanyu, Masayuki and Xie, Lin and Zhang, Yiding and Nagatsu, Kotaro and Suzuki, Hisashi and Ming-Rong, Zhang},
 issue = {29},
 journal = {Chemical Communications},
 month = {Feb},
 note = {Herein, a PD-L1 targeted native peptide was developed for PET imaging. 18F and 64Cu were utilized to label the peptide. To improve the pharmacokinetics and biodistribution of the tracers, the peptide was further pegylated to form star-like tetramers. Consequently, four tracers were synthesized with acceptable radiochemical characteristics and their in vivo pharmacokinetics and PD-L1 imaging capability were systematically evaluated. This proof-of-principle study
may provide new possibilities for PD-L1 PET imaging in cancers.},
 pages = {4162--4165},
 title = {Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation},
 volume = {55},
 year = {2019}
}