{"created":"2023-05-15T14:55:12.282613+00:00","id":75030,"links":{},"metadata":{"_buckets":{"deposit":"e20f5f5a-4b3c-4f13-8e6a-cd7d9cc473f9"},"_deposit":{"created_by":1,"id":"75030","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"75030"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00075030","sets":["10:28"]},"author_link":["742560","742554","742557","742552","742556","742553","742555","742558","742551","742559"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-04-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Hydroxyl radicals (*OH), hydrogen peroxide (H{sub}2{/sub}O{sub}2{/sub}), and superoxide (O{sub}2{/sub}{sup}*-{/sup}) are the important reactive oxygen species (ROS) for considering radio-biological effects. ROS generations in aqueous samples by X-ray or carbon-ion beams were quantified.\nAmount and distribution of *OH, H{sub}2{/sub}O{sub}2{/sub}, and total oxidation reactions were estimated by an electron paramagnetic resonance (EPR) spin-trapping, a modified spin-trapping, and spin-probing method, respectively.\n*OH generation was expected to be localized on the track/range of the radiation, and mM and M levels of *OH generation were observed. Total *OH generation was expected to be identical at the same dose even for X-ray or carbon-ion beam. Sparse *OH generation decreased with increasing LET. Carbon-ion beam produced denser H{sub}2{/sub}O{sub}2{/sub} compared with X-ray irradiation. H{sub}2{/sub}O{sub}2{/sub} generation decreased with the LET increasing, although the ratio of H{sub}2{/sub}O{sub}2{/sub} generation per oxygen consumed increased with LET. Total oxidation reactions decreased with increasing LET. Total oxidation reactions caused by low LET conditions decreased when the experiment was performed at low O{sub}2{/sub} concentration, while no difference was observed by high LET conditions.\nROS generation was not uniform and was LET dependent at the molecular level.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"9th Biennial Meeting for the Society for Free Radical Research Asia","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ken-ichiro, Matsumoto"}],"nameIdentifiers":[{"nameIdentifier":"742551","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nyui, Minako"}],"nameIdentifiers":[{"nameIdentifier":"742552","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ueno, Megumi"}],"nameIdentifiers":[{"nameIdentifier":"742553","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Yukihiro"}],"nameIdentifiers":[{"nameIdentifier":"742554","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakanishi, Ikuo"}],"nameIdentifiers":[{"nameIdentifier":"742555","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Kenichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"742556","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nyui, Minako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"742557","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ueno, Megumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"742558","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Yukihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"742559","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakanishi, Ikuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"742560","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"LET Dependent Generations of Reactive Oxygen Species and RedOx Reactions in an Aqueous Sample Irradiated by X-ray or Carbon-Ion Beam","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"LET Dependent Generations of Reactive Oxygen Species and RedOx Reactions in an Aqueous Sample Irradiated by X-ray or Carbon-Ion Beam"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-01-16"},"publish_date":"2019-01-16","publish_status":"0","recid":"75030","relation_version_is_last":true,"title":["LET Dependent Generations of Reactive Oxygen Species and RedOx Reactions in an Aqueous Sample Irradiated by X-ray or Carbon-Ion Beam"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T01:43:49.508225+00:00"}