{"created":"2023-05-15T14:55:04.513499+00:00","id":74853,"links":{},"metadata":{"_buckets":{"deposit":"8fada753-54ff-40d9-ad27-086921068613"},"_deposit":{"created_by":1,"id":"74853","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"74853"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00074853","sets":["1"]},"author_link":["929671","929672","929675","929678","929674","929676","929673","929677"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"1149","bibliographicPageStart":"1144","bibliographicVolumeNumber":"95","bibliographic_titles":[{"bibliographic_title":"International journal of radiation biology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: The aim of this study was to establish a new method of real-time, in vivo detection of radiation damage and recovery.\nMethods: The thymus was observed under fluorescent light in a green fluorescent protein transgenic medaka. After irradiation, medaka thymus images were analyzed to quantify the effects of radiation by measuring changes in thymus size. A single acute irradiation of X-rays (0–30 Gy) or heavy Fe ions (0–10 Gy) was delivered to the medaka. Images were captured 0, 1, 2, 3, 5, 7, 11, and 21 days after irradiation. Dose-response assessment was conducted to provide a direct measurement of the effects of the radiation.\nConclusion: A biomonitoring system to detect the effects of radiation in real time was established. Using this system, the threshold doses for the induction of thymic atrophy by acute X-rays and Fe ions were 2–5 Gy and 0.5–1 Gy, respectively. The Relative Biological Effectiveness (RBE) of Fe-ion to X-rays was estimated to be around 3. This system may be used to evaluate the risk from concurrent exposure to hazards, such as chemicals and radiation, and for aging research.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Taylor and Francis"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1080/09553002.2019.1589019","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.tandfonline.com/doi/full/10.1080/09553002.2019.1589019","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0955-3002","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Maruyama, Kouichi"}],"nameIdentifiers":[{"nameIdentifier":"929671","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwanami , Norimasa"}],"nameIdentifiers":[{"nameIdentifier":"929672","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takako, Maruyama-Hayakawa"}],"nameIdentifiers":[{"nameIdentifier":"929673","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Doi, Kazutaka"}],"nameIdentifiers":[{"nameIdentifier":"929674","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wang, Bing"}],"nameIdentifiers":[{"nameIdentifier":"929675","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kouichi, Maruyama","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"929676","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kazutaka, Doi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"929677","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Bing, Wang","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"929678","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-27"},"publish_date":"2019-02-27","publish_status":"0","recid":"74853","relation_version_is_last":true,"title":["A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:40:40.659960+00:00"}