{"created":"2023-05-15T14:53:51.359744+00:00","id":73334,"links":{},"metadata":{"_buckets":{"deposit":"c540df63-0cec-42f5-b18e-32d79cc594dc"},"_deposit":{"created_by":1,"id":"73334","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"73334"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00073334","sets":["10:27"]},"author_link":["722529","722528","722526","722527"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2018-09-16","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Nucleosomes create the diverse of the conformation of chromatin by the intra- and inter-nucleosome interactions. We analyzed these interactions using all-atom molecular dynamics simulations. As for the intra-nucleosomal interaction, the free energy profile for unwrapping the outer superhelical turn of nucleosomal DNA revealed that there are many potential paths to outer superhelicdal turn unwrapping, but the dominant path is likely asymmetric. As for the inter-nucleosomal interaction, the free energy profile for separating two nucleosomes revealed that H4 histone tails diversify the two nucleosomes’ orientation. These results provide insight into the construction, disruption, repositioning of nucleosomes to understand chromatin dynamics.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第56回日本生物物理学会年会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ishida, H."}],"nameIdentifiers":[{"nameIdentifier":"722526","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"H., Kono"}],"nameIdentifiers":[{"nameIdentifier":"722527","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石田 恒","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"722528","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河野 秀俊","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"722529","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Free energy profiles of the intra- and inter-nucleosomal interactions by all-atom molecular dynamics simulations","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Free energy profiles of the intra- and inter-nucleosomal interactions by all-atom molecular dynamics simulations"}]},"item_type_id":"10005","owner":"1","path":["27"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-09-25"},"publish_date":"2018-09-25","publish_status":"0","recid":"73334","relation_version_is_last":true,"title":["Free energy profiles of the intra- and inter-nucleosomal interactions by all-atom molecular dynamics simulations"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:30:27.744325+00:00"}