{"created":"2023-05-15T14:53:11.558954+00:00","id":72490,"links":{},"metadata":{"_buckets":{"deposit":"4fcd4ab5-a591-409b-91fd-073b31a475e8"},"_deposit":{"created_by":1,"id":"72490","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"72490"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00072490","sets":["10:28"]},"author_link":["713920","713922","713924","713923","713921"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017-10-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[11C]HCNは11C-ニトリル基だけでなく、その後の加水分解や還元により11C標識のカルボン酸、アミドおよびアミンを化合物に導入することができる有用な11C標識中間体である。現在[11C]HCNは主として[11C]CH4をプラチナ触媒下でアンモニアガスと900℃以上で反応させることにより製造されるが、そのためにはこの反応を行うための製造設備が必要になる。そこで、多くの11C製造施設で用いられている[11C]CH3Iから特別な設備が無くても簡便に[11C]HCNを製造する方法の開発を行った。\n[11C]CH3Iと(CH3)3NOをDMSO中で反応させ[11C]HCHOとし、これにHClのジオキサン溶液を添加したNH2OHのDMSO溶液を加えることで[11C]HCHOを[11C]HCNとした。反応温度、試薬量、反応時間などの諸条件を検討したところ、５分の反応で[11C]HCNが90％以上の放射化学的収率で生成される簡便な条件を見出した。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第57回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"菊池, 達矢"}],"nameIdentifiers":[{"nameIdentifier":"713920","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張, 明栄"}],"nameIdentifiers":[{"nameIdentifier":"713921","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"D., Gee Antony"}],"nameIdentifiers":[{"nameIdentifier":"713922","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菊池 達矢","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"713923","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 明栄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"713924","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"[11C]CH3I経由の[11C]HCNの簡便な合成法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"[11C]CH3I経由の[11C]HCNの簡便な合成法の開発"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-10"},"publish_date":"2017-10-10","publish_status":"0","recid":"72490","relation_version_is_last":true,"title":["[11C]CH3I経由の[11C]HCNの簡便な合成法の開発"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:39:15.898397+00:00"}