{"created":"2023-05-15T14:52:40.330514+00:00","id":71914,"links":{},"metadata":{"_buckets":{"deposit":"7d316c48-d944-4d9d-a40e-33176ced1b63"},"_deposit":{"created_by":1,"id":"71914","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"71914"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00071914","sets":["10:28"]},"author_link":["708231","708232"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-03-09","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"宇宙での長期滞在において、低フルエンス高LET放射線の人体影響の有無と防護は解明すべき重要な課題である。今年度は低線量率放射線被ばくの影響を、老化やストレスの影響を複合的に理解するための動物モデルとこれを用いた地上実験の系を確立した。がんの悪性化機構に関連の深いゲノム不安定性を哺乳動物の生体組織で評価できるRaDRマウス（Rosa26-Direct repeat-GFP transgenic）を用いた予備実験では、γ線の分割照射（1.8Gy x 4）から180日以内に被ばくした動物の約50%がリンパ腫を発症した。また、これらの腫瘍組織と被ばくした他の組織の一部で、GFP陽性細胞の有意な増加を観察した。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"新学術領域研究「宇宙に生きる」2016ワークショップ","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"平川, 博一"}],"nameIdentifiers":[{"nameIdentifier":"708231","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平川 博一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"708232","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"放射線誘発マウス胸腺腫とゲノム不安定性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"放射線誘発マウス胸腺腫とゲノム不安定性"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-03-15"},"publish_date":"2016-03-15","publish_status":"0","recid":"71914","relation_version_is_last":true,"title":["放射線誘発マウス胸腺腫とゲノム不安定性"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:45:57.477667+00:00"}