{"created":"2023-05-15T14:52:37.902900+00:00","id":71858,"links":{},"metadata":{"_buckets":{"deposit":"4657e46a-5da4-4e92-ae38-882349bf36d5"},"_deposit":{"created_by":1,"id":"71858","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"71858"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00071858","sets":["10:28"]},"author_link":["707550","707562","707561","707558","707552","707555","707557","707551","707559","707549","707548","707563","707553","707560","707554","707556"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-11-05","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"放射性金属核種の一つ64Cu（T1/2 = 12.7 h, + 17.4%, EC 43.6%, – 39.0%）は，キレートや抗体，ペプチド等と協同して，例えば低酸素部位のPETイメージング等をはじめとする臨床利用がなされている。64Cuは医療用小型加速器で製造可能，利便性の高い半減期など，今後も利用の発展が望まれる特徴に加え，β崩壊する特性を利用した標的アイソトープ治療（Targeted Radionuclide Therapy；TRT）への応用も期待できるといった非常に魅力的な核種と考えられる。\n主にイメージング用途を目的とした現在の小中規模の64Cu製造からTRTへの応用，即ち単回投与量として10 GBq前後が要求される大量製造を行う場合，治療という侵襲性の高い医療行為に耐えうる品質・不純物評価，及び製造環境の整備・効率化が，従来以上に重要となる。また大規模製造は核種頒布を可能にするなど，研究規模の拡大にも貢献出来るものと考えている。今回我々は，64Cuの大量製造に関わる装置開発とICP-MSによる不純物評価等について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第55回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 寿"}],"nameIdentifiers":[{"nameIdentifier":"707548","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"深田, 正美"}],"nameIdentifiers":[{"nameIdentifier":"707549","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大矢, 智幸"}],"nameIdentifiers":[{"nameIdentifier":"707550","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永津, 弘太郎"}],"nameIdentifiers":[{"nameIdentifier":"707551","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"峯岸, 克行"}],"nameIdentifiers":[{"nameIdentifier":"707552","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"破入, 正行"}],"nameIdentifiers":[{"nameIdentifier":"707553","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山崎, 慎之介"}],"nameIdentifiers":[{"nameIdentifier":"707554","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張, 明栄"}],"nameIdentifiers":[{"nameIdentifier":"707555","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 寿","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707556","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"深田 正美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707557","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大矢 智幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707558","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永津 弘太郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707559","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"峯岸 克行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707560","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"破入 正行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707561","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山崎 慎之介","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707562","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 明栄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"707563","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"臨床利用を目的とした64Cuの大量製造と品質評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"臨床利用を目的とした64Cuの大量製造と品質評価"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-11-19"},"publish_date":"2015-11-19","publish_status":"0","recid":"71858","relation_version_is_last":true,"title":["臨床利用を目的とした64Cuの大量製造と品質評価"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:46:34.474184+00:00"}