{"created":"2023-05-15T14:52:35.933172+00:00","id":71813,"links":{},"metadata":{"_buckets":{"deposit":"06dfd830-3307-43e0-bd22-08ba4ccf835d"},"_deposit":{"created_by":1,"id":"71813","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"71813"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00071813","sets":["10:28"]},"author_link":["706938","706922","706935","706936","706937","706932","706946","706950","706927","706948","706943","706947","706923","706933","706926","706921","706930","706928","706940","706920","706952","706944","706918","706939","706934","706925","706931","706919","706929","706924","706942","706941","706951","706949","706945"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-03-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"当所では1962年より他の機関に先駆けて大量のCVレベル、併せて1972年からはSPFレベルのマウス系統についても自家繁殖し、所内外の研究者に供給してきた。最盛期の1988年には44系統が維持され約37,000匹が生産されるまでに至った。しかし、諸般の事情により平成21年度をもって所内生産に終止符をうち、これらのマウス系統を理研BRCおよび熊大CARDへ寄託、日本エスエルシー（株）へ生産を委託することとなった。この48年の間にわが国の実験動物―動物実験を取り巻く諸環境は著しく変化し、特にマウスの生産に関連する技術には従来の遺伝学的、微生物学的分野以外にも生殖工学の分野での目覚しい発展があった。本報告会では①遺伝学的、微生物学的モニタリングシステム、②PCR法による遺伝子型判定、③人工哺育、④無菌動物の維持⑤胚・精子の凍結保存、体外授精⑥衛生管理⑦遺伝子改変マウスの作製等々当所が培ってきたマウスの生産に関連する諸技術を踏まえた今後の展開について述べてみたい。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第５回技術と安全の報告会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"早尾, 辰雄"}],"nameIdentifiers":[{"nameIdentifier":"706918","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上野, 渉"}],"nameIdentifiers":[{"nameIdentifier":"706919","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石田, 有香"}],"nameIdentifiers":[{"nameIdentifier":"706920","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小久保, 年章"}],"nameIdentifiers":[{"nameIdentifier":"706921","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塚本, 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