{"created":"2023-05-15T14:52:15.760956+00:00","id":71357,"links":{},"metadata":{"_buckets":{"deposit":"048ce32a-101d-4ed1-a4fb-df358f9cbcfb"},"_deposit":{"created_by":1,"id":"71357","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"71357"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00071357","sets":["10:28"]},"author_link":["701629","701626","701628","701627","701625","701630","701631","701624"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-06-03","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Carbon ion radiotherapy showed promising clinical outcomes in 57 patients with bone and STS during the phase I study (Kamada, JCO 22 4466-4471, 2002). This phase II study was planned thereafter. \nMethods: From April 2000 to February 2007, 301 lesions of 282 patients with bone and STS not suited for surgical resection were enrolled in this phase II study.  A total dose of 64.0 GyE in 16 fractions over 4 weeks was indicated for 15 lesions, that of 70.4 GyE for 276 and remaining 10 receiving 73.6 GyE. Mean age was 52 yrs, (range 12-85); site of origin was the pelvis in 74%, spine or para-spinous soft tissue in 20%, extremities in 5%: bone primary was in 78% and soft tissue in 22%; pathologic subtype in bone sarcoma was chordoma in 42%, chondrosarcoma in 21%, osteosarcoma in 21%; pathologic subtype in STS was MFH in 23%, MPNST in 21%, synovial sarcoma in 13%. \nResults: The 3- and 5-year overall actuarial survival rates were 68%  (95% Cl, 61%-75%) and 52% (95% C1, 43%-61%), respectively, and the actuarial overall local control rates were 85%  (95% C1, 80%- 90%), and 81% (95'%C1, 74%-88%) at 3 years and 5 years of follow-up, respectively. Overall toxicity was acceptable, with 2% skin/soft tissue late G3/4 toxicity. \nConclusions: Carbon ion radiotherapy shows a substantial local control in the patients with bone and soft tissue sarcomas not suited for surgical resection with acceptable morbidity.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"44th ASCO Annual Meeting","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"701624","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imai, Reiko"}],"nameIdentifiers":[{"nameIdentifier":"701625","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"701626","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Serizawa, Itsuko"}],"nameIdentifiers":[{"nameIdentifier":"701627","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"701628","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 礼子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"701629","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"701630","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"芹澤 慈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"701631","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Carbon Ion Radiotherapy for Bone and Soft Tissue Sarcomas","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon Ion Radiotherapy for Bone and Soft Tissue Sarcomas"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-14"},"publish_date":"2013-11-14","publish_status":"0","recid":"71357","relation_version_is_last":true,"title":["Carbon Ion Radiotherapy for Bone and Soft Tissue Sarcomas"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:52:11.935884+00:00"}