{"created":"2023-05-15T14:51:55.299336+00:00","id":70976,"links":{},"metadata":{"_buckets":{"deposit":"32c15b7f-c5c9-46ac-8bd8-54929b7662e1"},"_deposit":{"created_by":1,"id":"70976","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70976"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070976","sets":["10:28"]},"author_link":["697610","697603","697593","697596","697598","697605","697608","697604","697612","697606","697601","697613","697614","697597","697607","697594","697615","697611","697602","697609","697595","697600","697616","697599"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-10-31","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Various parameters are used for measuring tumor glucose metabolic activity with 18F-FDG PET\nincluding measuring the single maximum pixel value within the slice with highest radioactivity concentration\n(SUVmax) or placing a fixed ROI in the area of the tumor with the highest level of 18F-FDG uptake (SUVpeak),\nwhich it defines as the largest possible mean value of a 1 cm3 spherical VOI positioned within a tumor. SUVmax\nis avoided inter-observer variation, but a major drawback of this approach is its susceptibility to noise in the\ndata. SUVpeak is also removed inter-observer variation, and the averaging of multiple voxels reduces the\nsusceptibility to noise. In this study we determined which parameter of glucose metabolic activity provided the\nmost robust predictions of patient prognosis of pancreas cancer treated by carbon ion radiotherapy.\nMaterials and Methods: A total of 41 patients (28 males, 13 females; mean age, 65 + 8+- y) with pancreas cancer\nunderwent 18F-FDG PET/CT scan before carbon ion radiotherapy. The following parameters on the\npretreatment scans were measured: maximum standardized uptake value (SUVmax), two types of peak SUV\n(small: SUVpeak5, large: SUVpeak10), and average SUV (SUVave). SUVpeak5 and SUVpeak10 are measured\nusing spherical VOI with radius 5 mm and 10 mm, respectively. SUVave is an average pixel value of the circular\nROI with radius 5 mm within the slice with the highest radioactivity concentration. Correlation coefficients were\ncalculated for these parameters, and receiver operating characteristic (ROC) analysis was performed to\ncompare the prediction performance of each parameter for pancreas patients.\nResults: Pretreatment SUVmax, SUVpeak5, SUVpeak10, and SUVave averaged 6.6, 6.1, 5.1, and 6.0,\nrespectively. Correlation coefficients between all four parameters, SUVmax and SUVpeak5, SUVmax and\nSUVpeak10, SUVmax and SUVave, SUVpeak5 and SUVpeak10, SUVpeak5 and SUVave, SUVpeak10 and\nSUVave, were 0.995, 0.964, 0.994, 0.973, 0.995, and 0.969, respectively. The areas under the ROC curve of\nSUVmax, SUVpeak5, SUVpeak10, and SUVave were 0.69, 0.69, 0.92, and 0.70, respectively. ROC curves of\nSUVmax, SUVpeak5 and SUVave were closely approximated to each other, but the ROC curve of SUVpeak10\nwas different from others and much better than others.\nConclusions: Four FDG-PET uptake parameters were correlated closely. ROC analysis showed that\nSUVpeak10 was much better than others for prediction of pancreas patient prognosis. It seemed that relatively\nlarge sphere for calculating SUVpeak is better than small sphere if the tumor is large enough for setting the\nsphere within it.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Annual Congress of the European Association of Nuclear Medicine","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yoshikawa, Kyosan"}],"nameIdentifiers":[{"nameIdentifier":"697593","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohashi, Seiya"}],"nameIdentifiers":[{"nameIdentifier":"697594","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Toubaru, Sachiko"}],"nameIdentifiers":[{"nameIdentifier":"697595","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hasebe, Mitsuhiko"}],"nameIdentifiers":[{"nameIdentifier":"697596","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tamura, Katsumi"}],"nameIdentifiers":[{"nameIdentifier":"697597","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiraishi, Takahiro"}],"nameIdentifiers":[{"nameIdentifier":"697598","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanimoto, Katsuyuki"}],"nameIdentifiers":[{"nameIdentifier":"697599","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Shigeru"}],"nameIdentifiers":[{"nameIdentifier":"697600","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kandatsu, Susumu"}],"nameIdentifiers":[{"nameIdentifier":"697601","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukumura, Toshimitsu"}],"nameIdentifiers":[{"nameIdentifier":"697602","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saga, Tsuneo"}],"nameIdentifiers":[{"nameIdentifier":"697603","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"697604","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉川 京燦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697605","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大橋 靖也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697606","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"桃原 幸子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697607","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷部 充彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697608","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田村 克巳","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697609","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白石 貴博","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697610","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"谷本 克之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697611","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 滋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697612","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"神立 進","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697613","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福村 利光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697614","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697615","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697616","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Comparison of SUVmax and SUVpeak measuring FDG uptake for robust predictions of patient prognosis of pancreas cancer treated by carbon ion radiotherapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of SUVmax and SUVpeak measuring FDG uptake for robust predictions of patient prognosis of pancreas cancer treated by carbon ion radiotherapy"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-11-12"},"publish_date":"2012-11-12","publish_status":"0","recid":"70976","relation_version_is_last":true,"title":["Comparison of SUVmax and SUVpeak measuring FDG uptake for robust predictions of patient prognosis of pancreas cancer treated by carbon ion radiotherapy"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:56:38.063719+00:00"}