{"created":"2023-05-15T14:51:54.883798+00:00","id":70967,"links":{},"metadata":{"_buckets":{"deposit":"cfc563dd-b3d8-4dfb-8e12-8ca8c492acfe"},"_deposit":{"created_by":1,"id":"70967","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70967"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070967","sets":["10:28"]},"author_link":["697465","697467","697463","697469","697466","697470","697468","697464"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-10-21","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Ionizing radiation affects the mobility and the metastatic potential of tumors. These endpoints are regulated by specific adhesion molecules, such as the E-cadherins and lysyl oxidase (LOX). These molecules are downregulated E-cadherins) and upregulated (LOX) in hypoxia. \nTo study the adhesion molecules and to understand the underlying mechanisms that give to the cells the invasive phenotype, measurements of e-cadherin and LOX protein and gene expression have been performed in irradiated prostate cancer cells. \nX-rays induced a slight increase of E-cadherin after chronic hypoxic treatment (72 hours 0.5% O2) compared to normoxic cells. A low dose of carbon ion irradiation resulted in an overexpression of E-cadherin, while the opposite was found for X-rays. Implications of these results in radiotherapy will be discussed.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"The 10th International Symposium on Chromosomal Aberrations","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tinganelli, Walter"}],"nameIdentifiers":[{"nameIdentifier":"697463","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Durante, Marco"}],"nameIdentifiers":[{"nameIdentifier":"697464","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirayama, Ryoichi"}],"nameIdentifiers":[{"nameIdentifier":"697465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furusawa, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"697466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"697467","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ティンガネリ ワルター","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平山 亮一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤 佳也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"697470","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Expression of adhesion molecules in cancer cells after low- and high-LET radiation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Expression of adhesion molecules in cancer cells after low- and high-LET radiation"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-11-07"},"publish_date":"2012-11-07","publish_status":"0","recid":"70967","relation_version_is_last":true,"title":["Expression of adhesion molecules in cancer cells after low- and high-LET radiation"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:56:44.599765+00:00"}