@misc{oai:repo.qst.go.jp:00070751,
 author = {Matsufuji, Naruhiro and 松藤 成弘},
 month = {May},
 note = {Radiophotoluminescent glass dosimeter (RGD) is widely used as a dosimetric QA tool in conventional photon radiotherapy; however, its response for charged particles is poorly investigated nevertheless the interest toward the radiotherapy with light ions such as carbon is glowing for its superior dose conformity and high biological effectiveness even against radioresistant tumors. In this study, the response of the RGDs for the therapeutic carbon ions was studied for the application of the RGDs.
Experiment was carried out at the Heavy Ion Medical Accelerator in Chiba (HIMAC) of National Institute of Radiological Sciences in Chiba, Japan. The RGDs GD-302M-W manufactured by Asahi Glass Co., Ltd. were irradiated there by the therapeutic carbon beams as well as other species such as proton, helium, oxygen and iron beams for comparison.
The RGDs showed superior linear dose response for carbon ions in the dose range of 0.5 – 3.0 Gy; however, also showed strong decrease in response as LET (Linear Energy Transfer) of the beam increased. The extent of the drop relative to 60Co  rays exceeded 90 % near the Bragg peak where the LET was 160 keV/m approximately. The similar LET dependency was found for the other particle species and the extent of the drop was more significant for lighter particles at the same LET.
In order to understand the observed LET and particle species dependency of the RGD response, Local Effect Model (LEM) was used for the analysis. In the LEM the particle species dependency is considered to be evoked by the microscopic heterogeneity in energy deposition (track structure). The analysis of the response with the LEM, based on the radiation quality of the beam in the experimental conditions simulated by GEANT4, succeeded in reproducing the experimental results. The derived experimental as well as modeled response of the RGDs is useful for the application of the RGDs as a dosimeter for the therapeutic light ion beams., 13th International Congress of the International Radiation Protection Asspciation},
 title = {The Response of the Radiophotoluminescence Glass Dosimeter for Charged Particles and Its Microscopic Consideration},
 year = {2012}
}