@misc{oai:repo.qst.go.jp:00070732, author = {Shimada, Yoshiya and Nishimura, Mayumi and Kakinuma, Shizuko and Imaoka, Tatsuhiko and Takeda, Shino and Daino, Kazuhiro and Morioka, Takamitsu and Shang, Yi and Amasaki, Yoshiko and Iwata, Ken-ichi and Sawai, Tomoko and Tsuruoka, Chizuru and Hirano, Shinobu and Yamada, Yutaka and 島田 義也 and 西村 まゆみ and 柿沼 志津子 and 今岡 達彦 and 武田 志乃 and 臺野 和広 and 森岡 孝満 and 尚 奕 and 甘崎 佳子 and 岩田 健一 and 澤井 知子 and 鶴岡 千鶴 and 坂入 しのぶ and 山田 裕}, month = {Apr}, note = {With the advent of an era of low birthrate and prolonged longevity, concerns about the safety of fetuses and children have been growing. Programs to protect the health of fetuses and children from toxic agents are being instituted, particularly in the USA and Europe. These regulations are mainly directed at foodstuffs and chemicals. Recently, a progressive increase in medical uses of radiation for children has forced ICRP, IAEA and WHO to draft global initiatives on radiation protection of children. This group carries out studies to provide information on the risk of carcinogenesis due to radiation exposure during fetal and childhood periods, for which there are at present insufficient data. Using animal models, we study the effects of radiation exposure on lifespan shortening and cancer induction. Final goals of our research group are (1) to propose age-weighting factors and relative biological effectiveness (RBE) of heavy ions and neutrons for fetuses and children for radiation protection and (2) to clarify the biological basis of the susceptibility to radiation of fetal and infant tissues. We introduce here the whole picture of our research program, and describe the age dependence of lifespan shortening by gamma-irradiation in B6C3F1 mice, and unique response of infant tissues to radiation., International scientific conference on early exposure and childhood cancer}, title = {Radiobiology for Childrens Health Program}, year = {2012} }