{"created":"2023-05-15T14:51:42.536231+00:00","id":70686,"links":{},"metadata":{"_buckets":{"deposit":"fa7cadac-f983-4f8d-b719-e4e5706ff82a"},"_deposit":{"created_by":1,"id":"70686","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70686"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070686","sets":["10:28"]},"author_link":["694333","694332","694330","694334","694336","694331","694335","694338","694339","694337","694329","694340"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-11-19","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】炭素イオン線治療後の脳傷害の危険因子を明らかにする。\n【対象･方法】1997年4月から2009年2月までに頭蓋底腫瘍に対して炭素イオン線治療が行なわれ､2年以上MRIでの経過観察が可能であった38例を対象とした｡性別は男性19例、女性19例､年齢中央値は48歳。初回治療7例､術後31例であった｡７例に高血圧の既往を認めた。病理組織は脊索腫24例､軟骨肉腫5例、その他9例。炭素イオン線治療は16回/4週のスケジュールで行われ、総線量中央値は60.8GyE(48-60.8GyE)｡脳幹を除く脳をOARと設定しDVHパラメータを算出した。脳傷害のGradeはMRIを用いてLENT-SOMA tablesで評価した｡危険因子としてDVHパラメータ､患者因子を評価した。\n【結果】MRI観察期間中央値は67カ月。Grade2以上の脳傷害は15例に認められた。脳V20，30，40，50はGrade2以上の群でGrade1以下の群に比して有意に高値を示した。単変量解析ではV40,V50がGrade2以上の脳傷害の発生に関する有意な危険因子であった。多変量解析ではV50が危険因子として抽出された（p=0,006)。\n【結論】DVHパラメータは炭素イオン線治療による脳傷害の唯一の危険因子であった。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線腫瘍学会　第２４回学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小藤, 昌志"}],"nameIdentifiers":[{"nameIdentifier":"694329","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川, 安都佐"}],"nameIdentifiers":[{"nameIdentifier":"694330","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木, 亮"}],"nameIdentifiers":[{"nameIdentifier":"694331","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川, 陽"}],"nameIdentifiers":[{"nameIdentifier":"694332","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川, 貴迪"}],"nameIdentifiers":[{"nameIdentifier":"694333","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田, 正"}],"nameIdentifiers":[{"nameIdentifier":"694334","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤 昌志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694335","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694336","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694337","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川 陽","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694338","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川 貴迪","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694339","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"694340","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"炭素イオン線治療後の脳障害に関する危険因子","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"炭素イオン線治療後の脳障害に関する危険因子"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-02-22"},"publish_date":"2012-02-22","publish_status":"0","recid":"70686","relation_version_is_last":true,"title":["炭素イオン線治療後の脳障害に関する危険因子"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:00:03.170428+00:00"}