{"created":"2023-05-15T14:51:40.486913+00:00","id":70639,"links":{},"metadata":{"_buckets":{"deposit":"f44c96c0-d454-4ea1-b4a0-a4a61ba0a42a"},"_deposit":{"created_by":1,"id":"70639","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70639"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070639","sets":["10:28"]},"author_link":["693844","693848","693853","693851","693849","693845","693847","693843","693841","693852","693842","693850","693846"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-11-20","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The radical-scavenging rates of alpha-tocopherol and 6-chromanol derivatives with various substituents were examined in order to develop effective radioprotectors.  alpha-Tocopherol efficiently scavenged galvinoxyl radical (GO) with the second-order rate constant (k) of 3.3 x 10(3) M(-1) s(-1) in deaerated acetonitrile at 25 degrees C.  When the phytyl group at the C2 position in alpha-tocopherol was replaced by methyl group, no significant change was observed [k = 3.2 x 10(3) M(-1) s(-1)].  On the other hand, a carboxyl group at the C2 position significantly retarded the GO-scavenging rate [k = 4.9 x 10(2) M(-1) s(-1)].  Among the 6-chromanol derivatives, 8-amino-2,2-dimethylchroman-6-ol showed the highest GO-scavenging activity [k = 1.4 x 10(4) M(-1) s(-1)].  The smaller the calculated ionization potential by the density functional theory is, the stronger the GO-scavenging activity becomes.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"18th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM 2011)","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakanishi, Ikuo"}],"nameIdentifiers":[{"nameIdentifier":"693841","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inami, Keiko"}],"nameIdentifiers":[{"nameIdentifier":"693842","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohkubo, Kei"}],"nameIdentifiers":[{"nameIdentifier":"693843","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawashima, Tomonori"}],"nameIdentifiers":[{"nameIdentifier":"693844","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuhara, Kiyoshi"}],"nameIdentifiers":[{"nameIdentifier":"693845","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuzumi, Shunichi"}],"nameIdentifiers":[{"nameIdentifier":"693846","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Anzai, Kazunori"}],"nameIdentifiers":[{"nameIdentifier":"693847","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ozawa, Toshihiko"}],"nameIdentifiers":[{"nameIdentifier":"693848","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mochizuki, Masataka"}],"nameIdentifiers":[{"nameIdentifier":"693849","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Kenichiro"}],"nameIdentifiers":[{"nameIdentifier":"693850","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中西 郁夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693851","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川島 知憲","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693852","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本 謙一郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693853","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Radical-Scavenging Activity of 6-Chromanol Derivatives with Various Substituents","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Radical-Scavenging Activity of 6-Chromanol Derivatives with Various Substituents"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-11-24"},"publish_date":"2011-11-24","publish_status":"0","recid":"70639","relation_version_is_last":true,"title":["Radical-Scavenging Activity of 6-Chromanol Derivatives with Various Substituents"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:00:36.120362+00:00"}