{"created":"2023-05-15T14:51:38.571828+00:00","id":70595,"links":{},"metadata":{"_buckets":{"deposit":"904759dd-2dae-4e07-a6eb-f0728803dd64"},"_deposit":{"created_by":1,"id":"70595","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70595"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070595","sets":["10:28"]},"author_link":["693362","693358","693359","693368","693366","693363","693367","693361","693365","693360","693364","693357"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-10-29","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】頭頸部腺癌に対するＸ線治療成績は不良であり、手術不能例では長期予後が期待できないだけでなく、機能、整容面で患者のQOLは大幅に低下する。重粒子線はＸ線と比較して高い抗腫瘍効果と線量集中により、頭頸部腺癌の根治治療法となる可能性がある。今回頭頸部腺癌の重粒子線治療成績を評価した。【対象・方法】対象は1997年5月〜2010年6月に重粒子線治療が施行された頭頸部腺癌48例（男性29例、女性19例、年齢中央値は61歳）。原発部位は鼻腔・副鼻腔22例、眼窩8例、唾液腺7例、その他11例。初回治療例は31例（T分類はI期：1例、II期:2例、III期:6例、IV期23例）、術後再発9例、術後残存5例、化学療法後残存3例であった。3例に頸部リンパ節転移を認めた。炭素イオン線治療は16回/4週のスケジュールで行われ、30例は57.6GyE、18例は64.0GyEで治療された。【結果】全例治療を完遂した。観察期間中央値は42.5ヵ月(10.3-137.3ヵ月)。5年局所（照射野内）制御率は67.9％であった。5年全生存率、原病生存率、無病生存率はそれぞれ61.7％、63.0％、41.5%。晩期のGrade2以上の有害事象として視神経炎6例、脳炎1例、腐骨2例、粘膜潰瘍1例を高線量域内に認めた。【結論】重粒子線治療は頭頸部腺癌に対して有効な治療法であり、手術不能症例に対しても長期予後、QOLの維持が期待できる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第４９回日本癌治療学会学術集会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小藤, 昌志"}],"nameIdentifiers":[{"nameIdentifier":"693357","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川, 安都佐"}],"nameIdentifiers":[{"nameIdentifier":"693358","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木, 亮"}],"nameIdentifiers":[{"nameIdentifier":"693359","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川, 陽"}],"nameIdentifiers":[{"nameIdentifier":"693360","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川, 貴迪"}],"nameIdentifiers":[{"nameIdentifier":"693361","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田, 正"}],"nameIdentifiers":[{"nameIdentifier":"693362","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤 昌志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693363","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693364","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693365","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川 陽","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693366","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川 貴迪","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693367","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"693368","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"頭頸部線癌に対する重粒子線治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"頭頸部線癌に対する重粒子線治療"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-11-01"},"publish_date":"2011-11-01","publish_status":"0","recid":"70595","relation_version_is_last":true,"title":["頭頸部線癌に対する重粒子線治療"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:01:06.225135+00:00"}