@misc{oai:repo.qst.go.jp:00070426,
 author = {Tashima, Hideaki and Yoshida, Eiji and Kinouchi, Shoko and Nishikido, Fumihiko and Inadama, Naoko and Murayama, Hideo and Yoshikawa, Kyosan and Suga, Mikio and Haneishi, Hideaki and Yamaya, Taiga and et.al and 田島 英朗 and 吉田 英治 and 木内 尚子 and 錦戸 文彦 and 稲玉 直子 and 村山 秀雄 and 吉川 京燦 and 菅 幹生 and 羽石 秀昭 and 山谷 泰賀},
 month = {May},
 note = {We are developing the OpenPET, an open type positron emission tomography (PET), which has a physically opened field-of-view between detector rings. The OpenPET has great potential especially for the real-time tumor-tracking radiation therapy, if real-time imaging is realized. Disadvantages of the conventional tumor-tracking systems using implanted marker and x-ray imaging are invasiveness of implantation and risk of marker migration. On the other hand, the PET imaging is less invasive and detected positions and shapes are the same as the tumor. However, the real-time imaging of the PET is challenging task because of its computational burden for the image reconstruction. The aim of this study is to demonstrate the real-time OpenPET imaging by proposing a new system architecture and implementing it on a small prototype system. For real-time image reconstruction, we used recently developed fast PET reconstruction algorithm, 3D one-pass list-mode dynamic row-action maximum likelihood algorithm, and implemented on the GPU. In addition, we proposed a system architecture to stabilize the reconstruction speed by incorporating a data transfer control system which controls data flow and limits maximum data usage in the reconstruction step in every time frame. The proposed architecture was implemented on a single computer connected to the data acquisition system of the small OpenPET prototype. Demonstrational experiments of the developed system showed real-time imaging; tracking of a moving point source (1 MBq) was possible in 4D reconstructed images with a frame rate of 2 frames per second. The demonstration showed possibility of realizing the PET-guided tumor-tracking radiation therapy., PTCOG 50},
 title = {Toward real-time PET-guided tumor-tracking radiation therapy by the OpenPET},
 year = {2011}
}