{"created":"2023-05-15T14:51:30.320211+00:00","id":70406,"links":{},"metadata":{"_buckets":{"deposit":"66145ffe-f11f-4646-b208-632134eca38e"},"_deposit":{"created_by":1,"id":"70406","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70406"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070406","sets":["10:28"]},"author_link":["691348","691345","691350","691342","691344","691346","691343","691349","691347"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-09-19","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"メダカは古くから放射線影響が詳細に調べられた生物種であり、これまで致死線量をはじめとして様々な放射線影響研究のデータが蓄積しており、理科年表をはじめICRPレポートなどの多くの文献に記載されている。胸腺は放射線高感受性な臓器の一つとして知られているが、メダカでは1979年にGhoneumらにより、切片標本から体積を算出する系で放射線による胸腺の萎縮が調べられている (Ghoneum M. et al., J Fac. Sci. Univ. Tokyo, 1979)。\n　近年、徳島大学高浜研究室により開発された胸腺で特異的にGFPを発現するメダカ系統cab-Tg(rag1-egfp)は、生きたまま胸腺の形、大きさを見る事が出来る（Li J. et al., Journal of Immunology, 2007）。このメダカをナショナルバイオリソースから受入れ、放射線を照射後、蛍光観察による解析を行った。Ｘ線10Gyを照射すると、2日目には胸腺の萎縮が確認され、11日目にはほぼ胸腺の大きさは回復した。また、Ｘ線1Gy照射では非照射と比べ大きさに違いは見られなかった。このメダカ系統は一個体中の放射線障害を生きたまま殺さずに追って行く事が可能であり、放射線影響研究を解析する上で優れた系になりうる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第十六回小型魚類研究会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"丸山, 耕一"}],"nameIdentifiers":[{"nameIdentifier":"691342","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王, 冰"}],"nameIdentifiers":[{"nameIdentifier":"691343","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"針谷, まなみ"}],"nameIdentifiers":[{"nameIdentifier":"691344","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高浜, 洋介"}],"nameIdentifiers":[{"nameIdentifier":"691345","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川, 裕二"}],"nameIdentifiers":[{"nameIdentifier":"691346","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"丸山 耕一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"691347","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王 冰","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"691348","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"針谷 まなみ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"691349","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川 裕二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"691350","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"メダカ胸腺における放射線障害、回復の可視化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メダカ胸腺における放射線障害、回復の可視化"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-03-04"},"publish_date":"2011-03-04","publish_status":"0","recid":"70406","relation_version_is_last":true,"title":["メダカ胸腺における放射線障害、回復の可視化"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:03:18.989799+00:00"}