{"created":"2023-05-15T14:51:23.808653+00:00","id":70262,"links":{},"metadata":{"_buckets":{"deposit":"38ceef9c-5838-48bc-9668-ec2b7b0378d3"},"_deposit":{"created_by":1,"id":"70262","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"70262"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00070262","sets":["10:28"]},"author_link":["689892","689896","689890","689897","689891","689895","689894","689893"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-09-24","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"There is growing evidence that the stromal microenvironment can either positively or negatively regulate the neoplastic behavior of genetically aberrant cells through epigenetic modifications of gene expression. In this study, rat mammary tumors cells induced by the N-nitroso-N-methylurea were transplanted into the cleared fat pads of hosts, i.e., a normal mammary gland stromal microenvironment to see normalization of tumor cells. Consistent with the report by Maffini et al. (Am. J. Pathol., 167:1405, 2005), phenotypically normal ductal outgrowths were observed at from the injected site of mammary tumor cells at three months after transplantation. Currently, we are screening for epigenetically controlled genes involved in tumor normalization by means of both gene expression and CpG island microarrays.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第69回日本癌学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"臺野, 和広"}],"nameIdentifiers":[{"nameIdentifier":"689890","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今岡, 達彦"}],"nameIdentifiers":[{"nameIdentifier":"689891","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村, まゆみ"}],"nameIdentifiers":[{"nameIdentifier":"689892","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田, 義也"}],"nameIdentifiers":[{"nameIdentifier":"689893","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"臺野 和広","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"689894","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今岡 達彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"689895","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村 まゆみ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"689896","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田 義也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"689897","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"微小環境による乳がん表現型の正常化においてエピジェネティックに制御される遺伝子の探索","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"微小環境による乳がん表現型の正常化においてエピジェネティックに制御される遺伝子の探索"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-09-28"},"publish_date":"2010-09-28","publish_status":"0","recid":"70262","relation_version_is_last":true,"title":["微小環境による乳がん表現型の正常化においてエピジェネティックに制御される遺伝子の探索"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:04:59.870464+00:00"}