@misc{oai:repo.qst.go.jp:00070055,
 author = {Takashima, Yoshio and Nakata, Akifumi and Takada, Misaki and Akiyma, Miho and Yoshida, Mitsuaki and 高島 良生 and 中田 章史 and 川崎 実佐紀 and 穐山 美穂 and 吉田 光明},
 month = {Sep},
 note = {Accidental radiation exposure should be estimated as accurately as practicable. This aids physicians in deciding the appropriate medical procedures. Chromosomal aberrations in the peripheral lymphocytes are the most reliable indicators for biological dose estimation. The conventional method for estimating this dose uses score marker aberrations, such as dicentric and ring chromosomes in lymphocytes. However, because lymphocytes circulate in the peripheral blood, the dose estimated from these dicentric or ring values is the mean dose of whole-body cumulative radiation exposure. Therefore, in the case of partial body exposure, it is difficult to estimate the partial dose of radiation by this method. It is necessary to use the partial organ in order to estimate the dose of partial body exposure. The aim of this study is to establish an assay system to evaluate the dose of partial body exposure. For this purpose, we used the human hair root as the target organ and detected the indicators of dose estimation; further, we examined the method of culturing hair root cells for detecting chromosomal aberrations. The epilated hairs were dissected carefully, and single cells were isolated enzymatically. When the hair was irradiated with gamma radiation, DNA damage was detectable in the comet assay, and the cultured hair root cells were grown in vitro. These results suggest that dose estimation of partial body exposure is possible using hair root cells., BioDose 2008},
 title = {Potential of hair root cells for dose estimation in partial body exposure},
 year = {2008}
}