@misc{oai:repo.qst.go.jp:00069997,
 author = {今留, 香織 and 岩川, 眞由美 and 中渡, 美也子 and 中村, 悦子 and 今井, 高志 and 今留 香織 and 岩川 眞由美 and 中渡 美也子 and 中村 悦子 and 今井 高志},
 month = {Dec},
 note = {[Objectives] To establish a novel molecular classification of cervical cancer, we investigated intrinsic characteristics using expression profile. 
[Patients and methods] We recruited pre-treatment biopsy samples of 143 patients. We designed 3 sets of patients to confirm our findings by microarray analysis. Immunohisochemical analysis (IHA) were also performed.
[Results] The patients who all underwent radiotherapy. The statistical analysis for microarray data of 36 samples in 1st set formed mainly two clusters. Statistical test revealed 76 genes. Expression data of six representative genes, such as CK5, Nectin-1, CIDEB, AK091113.1 (SCC-type; up), TMEM98 and TACSTD1/EpCAM (AD; up) were confirmed by RT-PCR. IHA of EpCAM had strong positive immunoreactivity in AD (specificity; 90%, sensitivity; 80%), and its positive finding was related with prognosis (p = 0.048). 
[Conclusion] In this study, we report one of the most promising marker closely related with pathological diagnosis, EpCAM., 第32回日本分子生物学会年会},
 title = {子宮頸癌における分子診断マーカー、EpCAM},
 year = {2009}
}