{"created":"2023-05-15T14:51:09.249603+00:00","id":69928,"links":{},"metadata":{"_buckets":{"deposit":"adf446a6-3da7-4443-ac12-1d38a9d04122"},"_deposit":{"created_by":1,"id":"69928","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69928"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069928","sets":["10:28"]},"author_link":["686620","686618","686634","686629","686628","686633","686635","686631","686622","686625","686632","686626","686630","686619","686627","686621","686623","686624"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-10-30","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We studied DSB induction and rejoining in the clamped and non-clamped tumors after low- and high-LET radiations. SCCVII cells were transplanted into the right hind legs of C3H male mice. Conditioning irradiation with either 80 keV/μm carbon ions or 200 kVp X rays was delivered to the tumors at 5 mm diameter. Hypoxic cells were produced by clamping tumor-bearing mice 15min before irradiation in situ. Immediately after and 1 hr after irradiation, tumors were excised and rapidly cooled on ice. DSB in the tumors was analyzed by a static-field gel electrophoresis, and assayed for DSB induction and rejoining. The DSB immediately after X rays under normoxic condition was higher than under hypoxic condition. These damages in both tumor conditions were rejoined 60 to 70% within 1 hr in situ. The OER of DSB after X rays was 1.68 ± 0.31, and this value was not changed by 1 hr rejoining incubation (1.40 ± 0.26). On the other hand, no difference between X rays and carbon ions was found for the induction and rejoining of DSB. The rejoined fraction and the OER of DSB after carbon ions were similar to that after X rays. Additionally, the RBE of DSB immediately after and 1 hr after irradiation, these values were 0.9 to 1.3, and were not dependent on gases conditions. The yields of DSB induced by X rays in vivo might be similar to that after carbon ions, because the OER and RBE were not found a major difference.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"MICROS 2009 15th International Symposium on Microdosimetry","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirayama, Ryoichi"}],"nameIdentifiers":[{"nameIdentifier":"686618","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uzawa, Akiko"}],"nameIdentifiers":[{"nameIdentifier":"686619","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsumoto, Yoshitaka"}],"nameIdentifiers":[{"nameIdentifier":"686620","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noguchi, Miho"}],"nameIdentifiers":[{"nameIdentifier":"686621","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kase, Yuuki"}],"nameIdentifiers":[{"nameIdentifier":"686622","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Atsushi"}],"nameIdentifiers":[{"nameIdentifier":"686623","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okayasu, Ryuichi"}],"nameIdentifiers":[{"nameIdentifier":"686624","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koike, Sachiko"}],"nameIdentifiers":[{"nameIdentifier":"686625","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ando, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"686626","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furusawa, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"686627","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平山 亮一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686628","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鵜澤 玲子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686629","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本 孔貴","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686630","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加瀬 優紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686631","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 敦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686632","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡安 隆一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686633","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小池 幸子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686634","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤 佳也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686635","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"INDUCTION OF DNA DSB AND ITS REJOINING IN THE CLAMPED AND NON-CLAMPED TUMORS AFTER CARBON ION BEAMS COMPARED WITH X RAYS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"INDUCTION OF DNA DSB AND ITS REJOINING IN THE CLAMPED AND NON-CLAMPED TUMORS AFTER CARBON ION BEAMS COMPARED WITH X RAYS"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-11-09"},"publish_date":"2009-11-09","publish_status":"0","recid":"69928","relation_version_is_last":true,"title":["INDUCTION OF DNA DSB AND ITS REJOINING IN THE CLAMPED AND NON-CLAMPED TUMORS AFTER CARBON ION BEAMS COMPARED WITH X RAYS"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:08:48.836564+00:00"}