{"created":"2023-05-15T14:51:08.371575+00:00","id":69908,"links":{},"metadata":{"_buckets":{"deposit":"e68c9668-7955-4ebc-99be-bc93c9b0aa00"},"_deposit":{"created_by":1,"id":"69908","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69908"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069908","sets":["10:28"]},"author_link":["686400","686397","686402","686391","686403","686415","686392","686413","686406","686411","686408","686405","686401","686394","686389","686399","686412","686404","686414","686409","686398","686396","686407","686416","686393","686390","686395","686417","686410"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-10-14","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives\nFDG-PET provides quantitative information about tumor glucose utilization witch is useful for clinical diagnosis of tumor diseases. Standardized Uptake Value (SUV) is most commonly used for evaluation of tumor glucose utilization. But, SUV is affected by many factors that cannot be controlled or even taken into account. In that respect, brain reference index (BRI: ROI of tumor / ROI of cerebellum) is one of the novel quantitative approaches to eliminating the variety of factors that affect SUV. Meanwhile, a MRI pulse sequence could reveal the information about tissue cellularity. This information is useful to evaluate tumor nature. It suggests that it can be useful in the evaluation of malignancy in the lesions. We compared the role of glucose metabolism and cellularity for detection of pancreatic tumor malignancy.\nMaterials and Methods\nPET/CT: Toshiba Aquiduo, LSO crystals, 3D acquisition mode: 3min, OS-EM Iteration: 4, Subset: 14, Gaussian post filter: 8.0mm\n16 Multidetector-row CT, 120kV, Automatic exposure control (160 effective mAs), Helical pitch: 15mm/rot.\nMRI: GE healthcare Signa HDx 3T\nPre-surgery patients with primary pancreatic tumor underwent a whole body FDG-PET/CT and 3Tesla MRI. The malignancy or benignancy of excised specimens was pathologically confirmed in all cases. Tumor glucose utilization was evaluated with SUV and BRI in FDG-PET/CT study, and tumor cellularity was determined with MRI factors, apparent diffusion coefficient (ADC), T2 value and tumor to non-tumor ratio of proton density (TNRPD) in MRI study.\nADC were measured with a diffusion weighted image (DWI) using a spin-echo echo-planar sequence (TR=10s; TE=80ms; b factor=0, 400, 800,1200s/mm2).\nT2 value and proton density were measured with a spin-echo sequence (TR=3s; TE=40, 60, 80, 100ms).\nWe calculated TNRPD from proton density values of tumor and normal pancreas.\nWe compared these results with pathological findings.\nResults\nFDG uptake tended to be higher in malignant tumor than benign tumor. BRI seemed to distinguish malignant lesions from benign lesions more clearly than SUV alone. ADC was lower in malignant tumor than benign tumor. Malignant tumors showed higher TNRPD than benign tumors.\nConclusions\nThe tumor that shows high SUV, high BRI, low ADC, high TNRPD, high T2WI and high DWI indicate a high probability of pancreatic tumor malignancy. \nFDG-PET/CT in combination with MRI was superior to each modality alone for evaluating tumor malignant nature.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"The 2009 EANM Congress","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanimoto, Katsuyuki"}],"nameIdentifiers":[{"nameIdentifier":"686389","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshikawa, Kyosan"}],"nameIdentifiers":[{"nameIdentifier":"686390","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Obata, Takayuki"}],"nameIdentifiers":[{"nameIdentifier":"686391","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Toubaru, Sachiko"}],"nameIdentifiers":[{"nameIdentifier":"686392","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohashi, Seiya"}],"nameIdentifiers":[{"nameIdentifier":"686393","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hasebe, Mitsuhiko"}],"nameIdentifiers":[{"nameIdentifier":"686394","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiraishi, Takahiro"}],"nameIdentifiers":[{"nameIdentifier":"686395","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Kazuhiro"}],"nameIdentifiers":[{"nameIdentifier":"686396","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saga, Tsuneo"}],"nameIdentifiers":[{"nameIdentifier":"686397","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikehira, Hiroo"}],"nameIdentifiers":[{"nameIdentifier":"686398","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mizoe, Junetsu"}],"nameIdentifiers":[{"nameIdentifier":"686399","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"686400","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"686401","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Miyazaki, Masaru"}],"nameIdentifiers":[{"nameIdentifier":"686402","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"686403","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"谷本 克之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686404","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉川 京燦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686405","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小畠 隆行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686406","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"桃原 幸子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686407","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大橋 靖也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686408","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷部 充彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686409","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白石 貴博","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686410","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡邊 和洋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686411","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686412","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"池平 博夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686413","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江 純悦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686414","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686415","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686416","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"宮崎 勝","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686417","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Comparison of Glucose metabolism measured by FDG-PET/CT and Cellularity obtained from MRI for malignancy evaluation of pancreatic tumor","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of Glucose metabolism measured by FDG-PET/CT and Cellularity obtained from MRI for malignancy evaluation of pancreatic tumor"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-10-23"},"publish_date":"2009-10-23","publish_status":"0","recid":"69908","relation_version_is_last":true,"title":["Comparison of Glucose metabolism measured by FDG-PET/CT and Cellularity obtained from MRI for malignancy evaluation of pancreatic tumor"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:09:03.102913+00:00"}