{"created":"2023-05-15T14:51:07.507540+00:00","id":69888,"links":{},"metadata":{"_buckets":{"deposit":"d3c17aaf-643d-466b-9303-bc0469d7c12c"},"_deposit":{"created_by":1,"id":"69888","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69888"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069888","sets":["10:28"]},"author_link":["686141","686146","686144","686145","686143","686142"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-10-03","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Interleukin-9 (IL-9) is a multifunctional cytokine secreted from Th2 cell. Besides its role in immune and inflammatory responses, its growth promoting and antiapoptotic activities on multiple transformed cells suggest a potential role in tumorigenesis. We previously reported over-expression and activation of the receptor of IL-9 (IL-9R) in radiation-induced mouse T-cell leukemia (TL), which is an animal model of human T-cell acute lymphoblastic leukemia. In this study we established an Il9r-highly-expressing TL cell line, and examined the promoter activity with luciferase reporter assay. We found that promoter regulatory region was located at a 5` AT-rich region from -410 bp to -487 bp upstream translation start codon. EMSA and ChIP assay were also carried out to investigate the associated transcription factor(s).","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"68th Annual Meeting of the Japanese Cancer Association","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shang, Yi"}],"nameIdentifiers":[{"nameIdentifier":"686141","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kakinuma, Shizuko"}],"nameIdentifiers":[{"nameIdentifier":"686142","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimada, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"686143","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"尚 奕","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686144","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柿沼 志津子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686145","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田 義也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"686146","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"TRANSCRIPTIONAL REGULATION OF Il9r IN RADIATION-INDUCED MOUSE T-CELL LEYKEMIA CELL LINE","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"TRANSCRIPTIONAL REGULATION OF Il9r IN RADIATION-INDUCED MOUSE T-CELL LEYKEMIA CELL LINE"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-10-10"},"publish_date":"2009-10-10","publish_status":"0","recid":"69888","relation_version_is_last":true,"title":["TRANSCRIPTIONAL REGULATION OF Il9r IN RADIATION-INDUCED MOUSE T-CELL LEYKEMIA CELL LINE"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:09:16.993433+00:00"}