{"created":"2023-05-15T14:51:01.808635+00:00","id":69758,"links":{},"metadata":{"_buckets":{"deposit":"f356fc17-e929-4e22-a1b9-e3a22c00a325"},"_deposit":{"created_by":1,"id":"69758","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69758"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069758","sets":["10:28"]},"author_link":["684854","684855","684860","684861","684867","684869","684865","684856","684862","684864","684866","684859","684857","684858","684868","684863"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-05-20","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Numerous reports described the existence of radioinduced adaptive\nresponse (AR), a phenomenon of priming low-dose irradiation-induced\nresistance to subsequent irradiation at higher doses. AR research is of\ngreat concern as investigations on the conditions essential for AR induction\nprovide important scientific basis for risk estimates and offer significant\ninsight into the novel biological defense mechanisms. However, all the\ninvestigations at whole body level were performed using only low LET\nX-irradiations. In a series of study, possible AR induction by accelerated\nheavy ions (HI) is being attempted both in young adult female mice and in\nfetal mice of C57BL/6J Jms strain, using growth delay, hematopoietic damage\nand reduced survival in vivo, prenatal growth delay, malformation and death\nin utero as endpoints. Investigations are to verify if priming X-irradiation\ncould induce any resistance against the detrimental effects from high\nchallenging dose of HI, if priming irradiations from HI could induce an AR\nagainst the detrimental effects from high challenging dose of\nX-irradiations, and if an AR could be induced when both priming and\nchallenging irradiations are from HI. Three kinds of accelerated HI from\nmono beams of carbon, silicon and ion generated by HIMAC, with the LET\nvalues of about 15, 55, and 200 keV/micrometer respectively, are being\nexamined. Though the essential conditions vary on particle and/or LET,\nsuccessful induction of AR is induced for the first time using HI\nirradiations as either priming irradiation or challenging irradiation both\nin vivo and in utero. Details will be presented and discussed.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"2nd Asian Congress of Radiation Research (ACRR)","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Bing, Wang"}],"nameIdentifiers":[{"nameIdentifier":"684854","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Kaoru"}],"nameIdentifiers":[{"nameIdentifier":"684855","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Vares, Guillaume"}],"nameIdentifiers":[{"nameIdentifier":"684856","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shang, Yi"}],"nameIdentifiers":[{"nameIdentifier":"684857","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujita, Kazuko"}],"nameIdentifiers":[{"nameIdentifier":"684858","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ninomiya, Yasuharu"}],"nameIdentifiers":[{"nameIdentifier":"684859","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Eguchi-Kasai, Kiyomi"}],"nameIdentifiers":[{"nameIdentifier":"684860","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nenoi, Mitsuru"}],"nameIdentifiers":[{"nameIdentifier":"684861","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王 冰","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684862","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 薫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684863","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｇｕｉｌｌａｕｍｅ Ｖａｒｅｓ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"尚 奕","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684865","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田 和子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684866","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"二宮 康晴","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684867","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684868","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"根井 充","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"684869","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"INDUCTION OF RADIOADAPTIVE RESPONSE AT WHOLE BODY LEVEL: THE CASE OF HEAVY-ION IRRADIATIONS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"INDUCTION OF RADIOADAPTIVE RESPONSE AT WHOLE BODY LEVEL: THE CASE OF HEAVY-ION IRRADIATIONS"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-05-26"},"publish_date":"2009-05-26","publish_status":"0","recid":"69758","relation_version_is_last":true,"title":["INDUCTION OF RADIOADAPTIVE RESPONSE AT WHOLE BODY LEVEL: THE CASE OF HEAVY-ION IRRADIATIONS"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:10:45.757431+00:00"}