@misc{oai:repo.qst.go.jp:00069671,
 author = {Wael, Saleem and Abdulelah, Hussain MOBARAKI and Yoshida, Yukari and Suzuki, Yoshiyuki and Ohno, Tatsuya and Sakurai, Hideyuki and Nakano, Takashi and Ｗａｅｌ Ｓａｌｅｅｍ and アブドレラ フセイン  モバラキ and 吉田 由香里 and 鈴木 義行 and 大野 達也 and 櫻井 英幸 and 中野 隆史},
 month = {Oct},
 note = {(Purpose)
Treatment of the primary tumor with either surgery or radiotherapy can have unpredictable effects on metastases. The aim of this study was to investigate the effect of radiation fractionation on the motility, migration and invasiveness on cancer cells.
\n(Methods)
Three different cell lines were investigated; A549, U87 and WM793B. The total radiation dose was 5Gy as an acute and fractionations. The scratch motility assay and Western blot (PDK1, P75NGF and P53) were utilized within 24 hr after exposure to irradiation.
\n(Results)
After 12 and 24 h incubation showed that irradiation increased would healing activity and this increase was time dependant and invesrsely proportional to the dose rate of fractionation. Addtionally, all three protein makers showed a significant increase with fractionation compared to acute dose.
\n(Conclusions)
In this study, the enhancement of cell motility, migration and invasiveness by irradiation was observed and fractionation was correlated with over expression of both PDKI and P75NGF which were associated with cell migration and invasiveness., 日本放射線腫瘍学会第２１回学術大会},
 title = {Fraction enhances cells motility, migration and invasiveness},
 year = {2008}
}