{"created":"2023-05-15T14:50:46.363935+00:00","id":69403,"links":{},"metadata":{"_buckets":{"deposit":"64023719-75dd-43c4-b346-9187b5d39b68"},"_deposit":{"created_by":1,"id":"69403","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69403"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069403","sets":["10:28"]},"author_link":["681114","681130","681115","681112","681116","681120","681123","681127","681113","681124","681129","681131","681118","681121","681122","681128","681117","681119","681126","681125"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2007-05-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[目的] 早期発症および晩期発症のアルツハイマー病(AD)における脳内アミロイド沈着の差異について検討する。[対象および方法] 対照は、早期発症AD6例（男性6名、女性8例、MMSE 13+5）、晩期発症AD9例（男性2名、女性7例、MMSE 20+3）、健常者10名（男性6名、女性8例, MMSE 28+2）である。[11C]PIB –PET静注後90分間脳内放射能を測定し、血漿入力関数を用いてLogan plot解析して分布容積比（DVR）を算出し、脳内アミロイド結合の指標とした。[結果] 健常被験者では大脳皮質のDVRは1.2 + 0.1、早期発症ADでは1.8 + 0.1、晩期発症では1.8 + 0.1であった。脳内のアミロイド沈着の分布にも差がなかった。早期発症ADと晩期発症ADとの間にはアミロイド沈着には差がないことが明らかとなった。\n　","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第49回日本神経学会総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"篠遠, 仁"}],"nameIdentifiers":[{"nameIdentifier":"681112","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田, 斉"}],"nameIdentifiers":[{"nameIdentifier":"681113","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"三好, 美智恵"}],"nameIdentifiers":[{"nameIdentifier":"681114","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福士, 清"}],"nameIdentifiers":[{"nameIdentifier":"681115","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中, 典子"}],"nameIdentifiers":[{"nameIdentifier":"681116","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黄田, 常嘉"}],"nameIdentifiers":[{"nameIdentifier":"681117","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 康一"}],"nameIdentifiers":[{"nameIdentifier":"681118","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江, 俊章"}],"nameIdentifiers":[{"nameIdentifier":"681119","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 浩"}],"nameIdentifiers":[{"nameIdentifier":"681120","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"681121","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠 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康一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"681128","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江 俊章","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"681129","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"681130","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"681131","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"早期発症および晩期発症のアルツハイマー病における脳内アミロイドの沈着","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"早期発症および晩期発症のアルツハイマー病における脳内アミロイドの沈着"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-07-11"},"publish_date":"2008-07-11","publish_status":"0","recid":"69403","relation_version_is_last":true,"title":["早期発症および晩期発症のアルツハイマー病における脳内アミロイドの沈着"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:14:55.083141+00:00"}