{"created":"2023-05-15T14:50:38.064129+00:00","id":69241,"links":{},"metadata":{"_buckets":{"deposit":"5ab396ab-0778-430b-9b35-2ad31b093ea9"},"_deposit":{"created_by":1,"id":"69241","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"69241"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00069241","sets":["10:28"]},"author_link":["679467","679468","679475","679470","679474","679478","679466","679477","679476","679469","679465","679471","679472","679473"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2007-12-15","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"頭頸部粘膜悪性黒色腫は、悪性度が高く転移しやすい疾患である。炭素イオン線によ\nり高い局所制御を得られているが、遠隔転移を押さえ更なる長期生存を目的として、\n2001年よりDAV(DTIC,ACNU,VCR)化学療法併用炭素イオン線治療を行っている。今回\nDAV療法の効果について報告する。DAV療法は、第一コースと炭素イオン線治療の開始\nを一致させるように、1コース5日間、28日間隔で全5コース行った。DAV療法は全身状\n態を考慮し、20%までの減量投与や中止をした。炭素イオン線照射は57.6GyE/16回/4\n週間で行った。DAV投与は平均4コース施行可能であり、5コース完遂例は31例(60.8%)\nであった。副作用として嘔気・嘔吐は制吐剤により制御可能であった。骨髄抑制、肝\n障害はいずれもGrade3以下でありDAV療法中止後に回復した。腎障害は認めなかっ\nた。早期皮膚、粘膜反応はGrade3がそれぞれ1例(2%)、9例(18%)認めたが、いずれも\n晩期にはGrade2以下へ回復した。DAV療法による照射の有害事象の増加の印象はな\nかった。炭素イオン線単独治療(85例)での5年局所制御および生存率は、それぞれ\n75%、33%であったが、DAV併用炭素イオン線治療(51例)では83%、59%であった。悪性\n黒色腫のDAV併用炭素イオン線治療は完全な治療であり、遠隔転移の発現を押さえる\nことにより生存率の向上をはかることができる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線腫瘍学会　第２０回学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高木, 亮"}],"nameIdentifiers":[{"nameIdentifier":"679465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江, 純悦"}],"nameIdentifiers":[{"nameIdentifier":"679466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井, 博彦"}],"nameIdentifiers":[{"nameIdentifier":"679467","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳, 剛"}],"nameIdentifiers":[{"nameIdentifier":"679468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川, 安都佐"}],"nameIdentifiers":[{"nameIdentifier":"679469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"別所, 央城"}],"nameIdentifiers":[{"nameIdentifier":"679470","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"恩田, 健志"}],"nameIdentifiers":[{"nameIdentifier":"679471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679472","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江 純悦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679473","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679474","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳 剛","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679475","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679476","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"別所 央城","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679477","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"恩田 健志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"679478","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"頭頸部粘膜悪性黒色腫に対するＤＡＶ化学療法併用炭素イオン線治療−抗癌剤の効果解析−","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"頭頸部粘膜悪性黒色腫に対するＤＡＶ化学療法併用炭素イオン線治療−抗癌剤の効果解析−"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-12-19"},"publish_date":"2007-12-19","publish_status":"0","recid":"69241","relation_version_is_last":true,"title":["頭頸部粘膜悪性黒色腫に対するＤＡＶ化学療法併用炭素イオン線治療−抗癌剤の効果解析−"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:16:48.162067+00:00"}