{"created":"2023-05-15T14:50:26.370759+00:00","id":68978,"links":{},"metadata":{"_buckets":{"deposit":"abbea5ec-a488-4a42-873a-037811f7fe6d"},"_deposit":{"created_by":1,"id":"68978","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"68978"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00068978","sets":["10:28"]},"author_link":["677057","677055","677059","677062","677063","677054","677061","677060","677056","677058"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2007-06-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: Logan plot (LP) is a well-established algorithm for receptor imaging, however it requires a time history \nof radioactivity in plasma (pTAC) measured or a reference region where a target receptor is ignorable. Since the \nreference region is difficult to be located in the thoracoabdominal PET images, arterial blood sampling is \nnecessitated to be performed. Although pTAC can be obtained from the cardiac ventricle or aorta, it sufferes from \npartial volume effects, and some practical difficulties for ROI placement. We propose a new algorithm (EPISA) \nbased on LP using the intersectional searching scheme in a feature space describing the shape of measured PET \ndata (tTAC), and its usability is investigated for thoracoabdomen. Methods: An integral curve of pTAC is written \nas a sum of tTAC and its integral using LP. Moreover, the relationship means pTAC is located on the line between \ntTAC and its integral curve in a feature space. EPISA estimates an integral curve of pTAC as an intersectional \npoint among tTACs derived from multiple ROIs because pTAC is common among ROIs or voxels. In this study, a \n\\n11 \nthoracoabdominal dynamic PET data of [ C]TMSX, a radioligand for the adenosine A2A receptors, derived from \n\\nyoung normal subjects was applied to EPISA. Only the slices including the liver were utilized. Results: The \nestimated curves agreed with the measured version as shown in the figure in which the solid and dashed lines \ndenote an estimated and measured integral curves of pTACs, and the plots are data used in EPISA. EPISA was \nvery sensitive to the noise in tTACs, and noise reduction was important for reliable estimation before applying \nEPISA. Conclusions: We conclude that EPISA is applicable for estimation of the integral curve of the pTAC for \nthoracoabdominal PET data, and LP without arterial blood sampling can be attainable.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"54th SNM Annual Meeting　2007","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kimura, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"677054","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naganawa, Mika"}],"nameIdentifiers":[{"nameIdentifier":"677055","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oda, Keiichi"}],"nameIdentifiers":[{"nameIdentifier":"677056","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishii, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"677057","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishiwata, Kiichi"}],"nameIdentifiers":[{"nameIdentifier":"677058","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村 裕一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677059","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長縄 美香","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677060","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"織田 圭一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677061","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石井 賢二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677062","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石渡 喜一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"677063","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Omission of serial arterial blood sampling in thoracoabdominal PET images for Logan plot using intersectional searching algorithm for receptor imaging","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Omission of serial arterial blood sampling in thoracoabdominal PET images for Logan plot using intersectional searching algorithm for receptor imaging"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-06-26"},"publish_date":"2007-06-26","publish_status":"0","recid":"68978","relation_version_is_last":true,"title":["Omission of serial arterial blood sampling in thoracoabdominal PET images for Logan plot using intersectional searching algorithm for receptor imaging"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:19:54.444085+00:00"}