@misc{oai:repo.qst.go.jp:00068840, author = {Kandatsu, Susumu and Kishimoto, Riwa and Imai, Reiko and Kamada, Tadashi and Mizoe, Junetsu and Tsujii, Hirohiko and 神立 進 and 岸本 理和 and 今井 礼子 and 鎌田 正 and 溝江 純悦 and 辻井 博彦}, month = {Dec}, note = {Purpose: Chondrosarcoma and chordoma frequently have the same appearance on imaging studies. Both chordoma and chondrosacoma destroy bony structures with few calcification in tumor on CT imaging and high intensity on T2-weighted MR imaging with moderate staining after gadolinium administration. We studied differences between Chondrosarcoma and chordoma on diffusion-weighted imaging. Objects and Methods: Thirty-three patients (12with Chondrosarcoma and 21 with chordoma) underwent both conventional and diffusion-weighted MR imaging. MR imaging was performed at a 1.5 Tesla system with T1-weighted spin-echo sequence, gadolinium-enhanced T1-weighted spin-echo sequence, T2-weighted spin-echo sequence, and diffusion weighted sequence(b=0 and 1000 s/mm2).After creating apparent diffusion coefficients (ADC) maps, we compared the value of ADC of chondrosacoma with that of chordoma. Results: Both tumors have high intensity on T2-weighted MR image and moderate staining on T1-weighted MR image after gadolinium administration. Average of value of ADC is1.98 X 10(-3) mm2/s in Chondrosarcoma(N=12) and 1.24 X 10(-3) mm2/s in chordoma (N=21),respectively. Significant difference(t test; P=0.02)was recognized in value of ADC between Chondrosarcoma and chordoma. \nConclusion It is possible to differentiate Chondrosarcoma from chordoma using diffusion weighted-MR imaging. \nDiffusion weighted MR examination is recommended if high intensity tumor on T2 weighted MR image is observed in bone and soft tissue., 92nd Scientific Assembly and Annual Meeting}, title = {Differential Diagnosis of Chondrosarcoma from Chordoma using Diffusion-weighted MR Imaging}, year = {2006} }