{"created":"2023-05-15T14:50:13.181621+00:00","id":68678,"links":{},"metadata":{"_buckets":{"deposit":"6d6c101f-f145-4e33-9fb4-53b057629088"},"_deposit":{"created_by":1,"id":"68678","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"68678"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00068678","sets":["10:28"]},"author_link":["674008","674012","674001","674004","674014","674007","674002","674016","674006","674011","674015","674013","674017","674003","674005","674010","674009"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-09-08","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"妊娠15日目でのWistar ラット雄胎児の重粒子線での胎内被ばくの影響を、0.1 Gy か\nら2.0 Gy の線量範囲で、胎児生殖腺、出生後の精巣の発育、生殖力について調べた。\n比較としては、200 kVp のX 線を使った。2.0Gyでの離乳前の子供の死亡率は、ネオン\n線、炭素線、X線でそれぞれ、100%、18%、12%となった。ネオン線では0.1Gy程度の低\nい線量でも、離乳前の子供の死亡率や睾丸重量、体重に対する睾丸の重量の割合に有\n意な変化が見られた。炭素線やX線では、照射線量が0.5Gy以上になると、一般的に目\n立った効果を引き起こした。0.5Gy以上の照射は、線量依存的に生殖母細胞のアポトー\nシスを誘導し、出生前死亡を増加させ、睾丸の下降をおくらせ、睾丸重量を軽くし、\n体重に対する睾丸重量の割合を変化させ、精細管の奇形を増加させた。\n　1.0 Gyあるいは 1.5 Gyの照射を胎児期に受けると、雄の場合、 非照射の雌との交\n尾の成功率に顕著な減少が見られた。一方、胎児期に0.5Gy以上照射を受けた雄と非照\n射の雌との間の子供に、出生前死亡と離乳前の死亡率の有意な増加が見られた。これ\nらのことは、妊娠15日目での胎児への照射が、ラット雄胎児の発育や生後の精巣の成\n熟や生殖力に対して、広範囲にわたって著しく有害な影響を引き起こすことを示して\nいる。そしてその影響は、線量とLETに関係していた。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線影響学会　第49回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田中, 薫"}],"nameIdentifiers":[{"nameIdentifier":"674001","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王, 冰"}],"nameIdentifiers":[{"nameIdentifier":"674002","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村上, 正弘"}],"nameIdentifiers":[{"nameIdentifier":"674003","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井, 清美"}],"nameIdentifiers":[{"nameIdentifier":"674004","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野島, 久美恵"}],"nameIdentifiers":[{"nameIdentifier":"674005","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"尚, 奕"}],"nameIdentifiers":[{"nameIdentifier":"674006","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田, 和子"}],"nameIdentifiers":[{"nameIdentifier":"674007","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｈｅｒｖｅ, Ｃｏｆｆｉｇｎｙ"}],"nameIdentifiers":[{"nameIdentifier":"674008","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"早田, 勇"}],"nameIdentifiers":[{"nameIdentifier":"674009","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 薫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674010","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王 冰","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674011","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村上 正弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674012","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674013","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野島 久美恵","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674014","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"尚 奕","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674015","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田 和子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674016","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"早田 勇","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"674017","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"重粒子線によるラット胎児期被ばくの影響：精巣の発達と生殖力","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重粒子線によるラット胎児期被ばくの影響：精巣の発達と生殖力"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-09-15"},"publish_date":"2006-09-15","publish_status":"0","recid":"68678","relation_version_is_last":true,"title":["重粒子線によるラット胎児期被ばくの影響：精巣の発達と生殖力"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:23:23.522525+00:00"}