@misc{oai:repo.qst.go.jp:00068631, author = {Obata, Takayuki and Akine, Yoshihide and Ito, Hiroshi and Ikehira, Hiroo and Suhara, Tetsuya and Kanno, Iwao and et.al and 小畠 隆行 and 秋根 良英 and 伊藤 浩 and 池平 博夫 and 須原 哲也 and 菅野 巖}, month = {Sep}, note = {The thalamus is the central relay station for the brain, and there is evidence of its change with aging and laterality. The nuclei of the thalamus respectively comprise fibers connecting associated cortical regions, and it is known that abnormalities of the thalamus are correlated with abnormalities in cognition and behavior. Yet, little is known about the differences in the tissue characteristics of thalamic nuclei. We assessed regional characteristics in five major subregions (1-3) of both the left and right thalamus using diffusion-tensor imaging. We evaluated 16 healthy right-handed males aged under 40 years for the lateralities and regional differences of the thalamic subregions.The significant differences among the ractional anisotropy (FA) and mean diffusivity (MD) of the divided regions of the thalamus were obtained (F=44.1, df=9, 150. p<0.001. F=48.1, df=9, 150, P<0.001, ANOVA, respectively). The MD value of each subregion was lower in the left side than in the right side except for the posterior (Po) subregions. FA values of anterior lateral (AL) and posterior (Po) subregions were higher in the left side than in the right side.There were significant differences in FA and MD values among the subregions, respectively.These results suggest that both sides of thalamic nuclei behave independently, and that we should evaluate the respective microstructures of the thalamic nuclei. [References] 1. Buchsbaum, MS, et al. Am J Psychiatry. 153, 191-199, (1996). 2. Yasuno F, et al. Am J Psychiatry 161: 1016-1022, (2004)., the fifth annual meeting of the society for molecalar imaging}, title = {Laterality of Water Diffusion in Subsegments of Thalamus}, year = {2006} }