{"created":"2023-05-15T14:50:10.585103+00:00","id":68619,"links":{},"metadata":{"_buckets":{"deposit":"0ac5d9e9-e8eb-4e4f-b871-572e69c6799b"},"_deposit":{"created_by":1,"id":"68619","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"68619"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00068619","sets":["10:28"]},"author_link":["673447","673458","673454","673448","673446","673450","673457","673453","673451","673461","673459","673449","673452","673455","673456","673460","673444","673445"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-08-04","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It has been increasingly recognized that cancer patient's genetic information significantly influences therapeutic outcomes.  In this study, a novel experimental system was developed for estimating risk of radiation-induced normal tissue injury on individual cancer patients based on analysis of marker SNP genotypes, which had been screened by a large association study on genes involved in DNA damage repair, cell cycle control, redox regulation, inflammation and so on.  These marker SNPs were analyzed simultaneously using patient's blood-derived genomic DNA by a novel DNA chip method that provided optical detection of typing results.  The resulting spot images on the DNA chips were captured by a digital camera and processed by computerized tool to call genotype of SNPs.  The genotype information was then referred a database made by the foregoing large association study to statistically calculate risk of radiation-induced normal tissue injury.  This system does not require specific instruments and can be easily operated in a short time.  It is suitable to be used at laboratory of clinical hospitals.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Cancer Models & Mechanisms","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Michikawa, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"673444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Atsuko"}],"nameIdentifiers":[{"nameIdentifier":"673445","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noda, Shuhei"}],"nameIdentifiers":[{"nameIdentifier":"673446","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suga, Tomo"}],"nameIdentifiers":[{"nameIdentifier":"673447","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ootsuka, Yoshimi"}],"nameIdentifiers":[{"nameIdentifier":"673448","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawai, Seiko"}],"nameIdentifiers":[{"nameIdentifier":"673449","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugahara, Keisuke"}],"nameIdentifiers":[{"nameIdentifier":"673450","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwakawa, Mayumi"}],"nameIdentifiers":[{"nameIdentifier":"673451","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imai, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"673452","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"道川 祐市","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673453","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川 敦子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673454","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野田 秀平","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673455","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅 智","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673456","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荘司 好美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673457","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川井 聖子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673458","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅原 圭亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673459","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩川 眞由美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673460","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 高志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"673461","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Risk estimation of radiation-induced normal tissue injury on cancer patients by convenient analysis of marker SNPs","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Risk estimation of radiation-induced normal tissue injury on cancer patients by convenient analysis of marker SNPs"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-08-07"},"publish_date":"2006-08-07","publish_status":"0","recid":"68619","relation_version_is_last":true,"title":["Risk estimation of radiation-induced normal tissue injury on cancer patients by convenient analysis of marker SNPs"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:24:06.405910+00:00"}